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使用升级版FS200飞秒激光的飞秒激光制瓣准分子原位角膜磨镶术后彩虹眩光的高发生率。

High incidence of rainbow glare after femtosecond laser assisted-LASIK using the upgraded FS200 femtosecond laser.

作者信息

Zhang Yu, Chen Yue-Guo

机构信息

Department of Ophthalmology, Peking University Third Hospital, 49 North Huayuan Road, Haidian District, Beijing, 100191, China.

出版信息

BMC Ophthalmol. 2018 Mar 5;18(1):71. doi: 10.1186/s12886-018-0734-1.

DOI:10.1186/s12886-018-0734-1
PMID:29506498
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5838985/
Abstract

BACKGROUND

To compare the incidence of rainbow glare (RG) after femtosecond laser assisted-LASIK (FS-LASIK) using the upgraded FS200 femtosecond laser with different flap cut parameter settings.

METHODS

A consecutive series of 129 patients (255 eyes) who underwent FS-LASIK for correcting myopia and/or astigmatism using upgraded WaveLight FS200 femtosecond laser with the original settings was included in group A. Another consecutive series of 129 patients (255 eyes) who underwent FS-LASIK using upgraded WaveLight FS200 femtosecond laser with flap cut parameter settings changed (decreased pulse energy, spot and line separation) was included in group B. The incidence and fading time of RG, confocal microscopic image and postoperative clinical results were compared between the two groups.

RESULTS

There were no differences between the two groups in age, baseline refraction, excimer laser ablation depth, postoperative uncorrected visual acuity and refraction. The incidence rate of RG in group A (35/255, 13.73%) was significantly higher than that in group B (4/255, 1.57%) (P < 0.05). The median fading time was 3 months in group A and 1 month in group B (P > 0.05).The confocal microscopic images showed wider laser spot spacing in group A than group B. The incidence of RG was significantly correlated with age and grouping (P < 0.05).

CONCLUSIONS

The upgraded FS200 femtosecond laser with original flap cut parameter settings could increase the incidence of RG. The narrower grating size and lower pulse energy could ameliorate this side effect.

摘要

背景

比较使用升级后的FS200飞秒激光并采用不同瓣切参数设置进行飞秒激光制瓣准分子原位角膜磨镶术(FS-LASIK)后彩虹眩光(RG)的发生率。

方法

A组纳入连续129例患者(255只眼),他们使用升级后的威视FS200飞秒激光并采用原始设置进行FS-LASIK以矫正近视和/或散光。B组纳入连续129例患者(255只眼),他们使用升级后的威视FS200飞秒激光并采用改变后的瓣切参数设置(降低脉冲能量、光斑和线间距)进行FS-LASIK。比较两组之间RG的发生率和消退时间、共焦显微镜图像及术后临床结果。

结果

两组在年龄、基线屈光、准分子激光消融深度、术后裸眼视力和屈光方面无差异。A组RG的发生率(35/255,13.73%)显著高于B组(4/255,1.57%)(P<0.05)。A组的中位消退时间为3个月,B组为1个月(P>0.05)。共焦显微镜图像显示A组的激光光斑间距比B组宽。RG的发生率与年龄和分组显著相关(P<0.05)。

结论

采用原始瓣切参数设置的升级后FS200飞秒激光会增加RG的发生率。更窄的光栅尺寸和更低的脉冲能量可改善这种副作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b461/5838985/ff0c013b9a8d/12886_2018_734_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b461/5838985/9fe9dd0e42c6/12886_2018_734_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b461/5838985/b850b97b604d/12886_2018_734_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b461/5838985/d35ca660bfb4/12886_2018_734_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b461/5838985/4ca0bd3c89b3/12886_2018_734_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b461/5838985/ff0c013b9a8d/12886_2018_734_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b461/5838985/9fe9dd0e42c6/12886_2018_734_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b461/5838985/b850b97b604d/12886_2018_734_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b461/5838985/d35ca660bfb4/12886_2018_734_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b461/5838985/4ca0bd3c89b3/12886_2018_734_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b461/5838985/ff0c013b9a8d/12886_2018_734_Fig5_HTML.jpg

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Comparative study of stromal bed of LASIK flaps created with femtosecond lasers (IntraLase FS150, WaveLight FS200) and mechanical microkeratome.飞秒激光(IntraLase FS150、WaveLight FS200)与机械角膜刀制作 LASIK 瓣基质床的对比研究。
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