Chen Huangguan, Han Jianwei, Wang Limin
Key Laboratory for Advanced Materials, Institute of Fine Chemicals, School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China.
Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, The Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
Beilstein J Org Chem. 2018 Feb 6;14:354-363. doi: 10.3762/bjoc.14.23. eCollection 2018.
With a strategy of the formation of benzynes by using diaryliodonium salts, a cycloaddition reaction of -arylpyrroles with benzynes was reported. A wide range of bridge-ring amines with various substituents have been synthesized in moderate to excellent yields (35-96%). Furthermore, with a catalytic amount of TsOH·HO, these amines can be converted into the corresponding -phenylamine derivatives easily, which are potentially useful in photosensitive dyes.
通过使用二芳基碘鎓盐形成苯炔的策略，报道了芳基吡咯与苯炔的环加成反应。已以中等至优异的产率（35 - 96%）合成了多种带有不同取代基的桥环胺。此外，在催化量的对甲苯磺酸一水合物存在下，这些胺可以轻松转化为相应的芳基苯胺衍生物，它们在光敏染料方面具有潜在用途。
