Boada Luis D, Sangil Marta, Alvarez-León Eva E, Hernández-Rodríguez Guayarmina, Henríquez-Hernández Luis Alberto, Camacho María, Zumbado Manuel, Serra-Majem Lluis, Luzardo Octavio P
Toxicology Unit, Clinical Sciences Department, Universidad de Las Palmas de Gran Canaria (Spain), Instituto Canario de Investigación del Cáncer (ICIC), and Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition (CIBERObn), Las Palmas de Gran Canaria, Spain.
Toxicology Unit, Clinical Sciences Department, Universidad de Las Palmas de Gran Canaria (Spain), Instituto Canario de Investigación del Cáncer (ICIC), and Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition (CIBERObn), Las Palmas de Gran Canaria, Spain; Preventive Medicine Unit, Clinical Sciences Department, Universidad de Las Palmas de Gran Canaria, Instituto Canario de Investigación del Cáncer (ICIC), and Spanish Biomedical Research Centre in the Physiopathology of Obesity and Nutrition (CIBERObn), Las Palmas de Gran Canaria, Spain.
Chemosphere. 2014 Nov;114:121-8. doi: 10.1016/j.chemosphere.2014.03.126. Epub 2014 May 13.
The level of contamination with persistent organic pollutants (POPs) and dietary habits and food consumption was extensively studied in the population from the Canary Islands (Spain). Because foodstuffs of animal origin are well known to be prominent contributors to these contaminants, the current study aimed to assess the role of the dietary intake of animal products as a probability factor for increased serum POPs. The intake of animal products (dietary variables) as a determining factor for serum POP levels was investigated using multivariate statistical models. Our results showed that while poultry, rabbit, and cheese consumption increases the probability of having high levels of non-DDT-derivative pesticides, sausage, yogurt, lard, and bacon consumption decreases the probability of having high levels of these pesticides. In addition, poultry, rabbit, eggs, cream, and butter consumption increased the probability of having detectable levels of marker PCB, while dairy desserts decreased the probability of having detectable levels of these PCBs. On the contrary, sausage and meat consumption increased the probability of having detectable levels of dioxin-like PCBs (DL-PCBs). The current results confirm that dietary intake of foodstuffs of animal origin is a relevant risk factor for the accumulation of POPs (and therefore their serum levels). Our study indicates that the analysis of dietary patterns may be useful for identifying those individuals that will probably present a high body burden of POPs. Because POPs can exert deleterious effects on human health, the identification of populations at risk of being highly contaminated is mandatory in order to implement policies that minimize the exposure to these compounds.
对西班牙加那利群岛人群中持久性有机污染物（POPs）的污染水平、饮食习惯和食物消费情况进行了广泛研究。由于动物源性食品是这些污染物的主要来源，因此本研究旨在评估动物产品的膳食摄入量作为血清中POPs增加的一个概率因素的作用。使用多元统计模型研究了动物产品摄入量（膳食变量）作为血清POP水平的决定因素。我们的结果表明，食用家禽、兔肉和奶酪会增加体内非滴滴涕衍生农药含量高的概率，而食用香肠、酸奶、猪油和培根会降低体内这些农药含量高的概率。此外，食用家禽、兔肉、鸡蛋、奶油和黄油会增加体内可检测到标记多氯联苯（PCB）的概率，而食用奶类甜点会降低体内可检测到这些PCB的概率。相反，食用香肠和肉类会增加体内可检测到二恶英类多氯联苯（DL-PCBs）的概率。目前的结果证实，动物源性食品的膳食摄入量是POPs积累（以及因此其血清水平）的一个相关风险因素。我们的研究表明，分析饮食模式可能有助于识别那些体内可能有高POPs负担的个体。由于POPs会对人类健康产生有害影响，因此必须识别出有高污染风险的人群，以便实施将接触这些化合物降至最低的政策。
