University of North Carolina, Chapel Hill, North Carolina, USA.
The Desmond Tutu HIV Centre, University of Cape Town, Cape town, South Africa.
Curr Opin HIV AIDS. 2018 May;13(3):265-273. doi: 10.1097/COH.0000000000000453.
Many of the almost 2 million HIV infections that occurred globally in the last year occurred among adolescents and young people, particularly those from East and Southern Africa and within key populations. Global HIV epidemic control will require that new infections among these youth populations be curtailed. This review examines the most effective prevention approaches to reach these adolescent populations in the next 5 years.
Adolescents are in transition and are developmentally unique. They have specific needs and challenges, which if not addressed will result in less than successful interventions. Tailored, layered, combination prevention packages that take into account specific adolescent needs and involve biomedical, behavioural and structural components are recommended. These packages should be designed for and with the meaningful input of adolescents, and involve their peers in their implementation and execution. Where possible, age-appropriate health and social interventions that go beyond HIV should be bundled and offered in a variety of community-based venues that are already acceptable to and frequented by adolescents.
It is urgent that we reach adolescents globally with the most effective HIV prevention approaches. HIV prevention investment in this population has immediate and longer-term benefits.
在过去一年中,全球发生的近 200 万例艾滋病病毒感染中,有许多发生在青少年和年轻人中,特别是来自东非和南部非洲以及关键人群中的青少年和年轻人。全球艾滋病毒疫情控制需要遏制这些青年人群中的新感染。这篇综述探讨了在未来 5 年内最有效的预防方法,以接触到这些青少年群体。
青少年正处于过渡期,在发展上具有独特性。他们有特定的需求和挑战,如果这些需求和挑战得不到解决,干预措施将不会取得成功。建议采用量身定制、分层、组合的预防方案,考虑到具体的青少年需求,并涉及生物医学、行为和结构组成部分。这些方案应由青少年参与设计和实施,并让他们的同龄人参与方案的实施和执行。在可能的情况下,应将与艾滋病病毒无关的、适合年龄的卫生和社会干预措施捆绑在一起,并在已经被青少年接受和经常光顾的各种社区场所提供。
我们迫切需要用最有效的艾滋病病毒预防方法接触全球的青少年。在这一人群中进行艾滋病病毒预防投资具有直接和长期的益处。