Podhaisky H, Hänsgen K, Bartlitz C
Z Gesamte Inn Med. 1987 Feb 1;42(3):79-81.
Nitrates decrease the tonus of the smooth vascular musculature and cause a vasodilation also in the region of the peripheral arterial system. This was shown after sublingual administration of glycerol trinitrate in test persons with a healthy vessel and patients with arterial occlusive disease in stage II. A significant change of the poststenotic systolic pressure and the influence on the parameters of the rheographic volume pulse curve developed. The peripheral effects of nitrate are used in the angiological functional diagnostics. They are of importance for the medicamentous therapy of vasospastically and organically disturbances of the arterial blood supply.
硝酸盐可降低血管平滑肌的紧张度，并在外周动脉系统区域引起血管舒张。这在健康血管的测试者以及II期动脉闭塞性疾病患者舌下含服硝酸甘油后得到证实。狭窄后收缩压发生了显著变化，并且对血流图容积脉搏曲线的参数产生了影响。硝酸盐的外周效应被用于血管学功能诊断。它们对于动脉血液供应的血管痉挛性和器质性紊乱的药物治疗具有重要意义。
