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2003 年至 2014 年颈椎神经根病前路颈椎间盘切除术和融合术与后路颈椎侧块切除术的比较:利用、成本和不良事件。

Comparison of Anterior Cervical Discectomy and Fusion to Posterior Cervical Foraminotomy for Cervical Radiculopathy: Utilization, Costs, and Adverse Events 2003 to 2014.

机构信息

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

Department of Public Health Sciences, The University of Chicago, Chicago, Illinois.

出版信息

Neurosurgery. 2019 Feb 1;84(2):413-420. doi: 10.1093/neuros/nyy051.

Abstract

BACKGROUND

Surgery for cervical radiculopathy is often approached by either anterior cervical discectomy and fusion (ACDF) or posterior cervical foraminotomy (PCF). ACDF is more common; however, recent single center studies suggest comparable efficacy and significant cost savings with PCF in appropriately selected patients.

OBJECTIVE

To compare utilization, adverse events, and costs for each approach from a national perspective.

METHODS

Adults undergoing single level ACDF or PCF for cervical radiculopathy were included from a US commercial health insurance claims database spanning 2003 to 2014. Outcomes consisted of mortality, adverse events, length of stay, and total payments to the health provider. Propensity score matching balanced the groups on observed baseline covariates.

RESULTS

The PCF cohort comprised 4851 subjects and the ACDF cohort included 46 147. A greater proportion of PCF cases were discharged on the same day (70.6% vs 46.1%; P < .001). Mortality (0.1/1000, P = .012), vascular injury (0.2/1000, P = .001), postoperative dysphagia/dysphonia (14.5/1000, P < .001), cutaneous cerebrospinal fluid leak (0.2/1000, P = .002), and deep venous thrombosis (0.9/1000, P = .013) occurred more frequency in the ACDF cohort. Conversely, wound infections (14.6/1000, P < .001) and 30-d readmissions (9.8/1000, P < .001) were more frequent in the PCF cohort. Mean unadjusted total payments for the PCF cohort were $15 281 ± 12 225 and $26 849 ± 16 309 for ACDF. Matched difference was -$11 726 [95% confidence interval: -$12 221, -$11 232, P < .001] favoring PCF.

CONCLUSION

Within the inherent limitations of administrative data, our findings suggest an opportunity for value improvement in managing cervical radiculopathy and indicate a need for large-scale comparative study of clinical outcomes and costs.

摘要

背景

颈椎神经根病的手术治疗通常采用前路颈椎间盘切除融合术(ACDF)或后路颈椎侧方减压术(PCF)。ACDF 更为常见;然而,最近的单中心研究表明,在适当选择的患者中,PCF 的疗效相当,且可显著节省成本。

目的

从全国角度比较两种方法的利用率、不良事件和成本。

方法

从 2003 年至 2014 年美国商业健康保险索赔数据库中纳入接受单节段 ACDF 或 PCF 治疗颈椎神经根病的成年人。结果包括死亡率、不良事件、住院时间和向医疗服务提供者支付的总费用。倾向评分匹配使两组在观察到的基线协变量上达到平衡。

结果

PCF 组包含 4851 例患者,ACDF 组包含 46147 例患者。PCF 组中更多的病例在同一天出院(70.6% vs 46.1%;P<.001)。ACDF 组的死亡率(0.1/1000,P=0.012)、血管损伤(0.2/1000,P=0.001)、术后吞咽困难/声音嘶哑(14.5/1000,P<.001)、皮肤脑脊液漏(0.2/1000,P=0.002)和深静脉血栓形成(0.9/1000,P=0.013)的发生率更高。相反,PCF 组的伤口感染(14.6/1000,P<.001)和 30 天再入院率(9.8/1000,P<.001)更高。PCF 组的未调整平均总支付额为 15281±12225 美元,ACDF 组为 26849±16309 美元。匹配差异为-11726 美元[-12221,-11232,P<.001],有利于 PCF。

结论

在行政数据固有的局限性内,我们的发现表明在管理颈椎神经根病方面有改善价值的机会,并表明需要对临床结果和成本进行大规模的比较研究。

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