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临床实践中的食管支架置入术:概述

Esophageal Stenting in Clinical Practice: an Overview.

作者信息

Vermeulen Bram D, Siersema Peter D

机构信息

Department of Gastroenterology and Hepatology, Radboud University Medical Center, Geert Grooteplein-Zuid 8 (route 455), 6500, HB, Nijmegen, the Netherlands.

出版信息

Curr Treat Options Gastroenterol. 2018 Jun;16(2):260-273. doi: 10.1007/s11938-018-0181-3.

Abstract

OPINION STATEMENT

PURPOSE OF REVIEW: Esophageal stents are used in clinical practice for endoscopic treatment of a wide variety of esophageal diseases and conditions. This review provides key principles and a literature update on the utility and limitations of esophageal stenting in clinical practice.

RECENT FINDINGS

Indications for esophageal stenting can be subdivided into two groups. The first group consists of patients with malignant or benign dysphagia, in which an esophageal stent restores luminal patency. In the past years, temporary stent placement has increasingly been used in the therapeutic management of refractory benign esophageal strictures. When endoscopic repeated bougie dilation and other endoscopic treatment modalities have failed, an esophageal stent could be considered. Based on the literature, a fully covered self-expandable metal stent may be the preferred choice for the treatment of both malignant and benign dysphagia. The second group consists of patients with leakage from the esophageal lumen into the surrounding tissue. Esophageal leakage can be subdivided into three forms, benign esophageal perforations (iatrogenic and spontaneous), anastomotic leakage after reconstructive esophageal surgery, and fistula. In a carefully selected group of patients, a covered esophageal stent may be used for sealing off the leakage, thereby preventing further contamination of the tissue surrounding the defect. The past few years, several validated prediction tools have been developed that may assist clinicians in the selection of patients eligible for esophageal stent placement. Based on retrospective studies and expert opinion, a partially or fully covered self-expandable metal stent may have a role in treatment of esophageal leakage. Research do date supports the utilization of esophageal stents for the treatment of malignant or benign dysphagia and esophageal leakage.

摘要

观点陈述

综述目的:食管支架在临床实践中用于多种食管疾病和病症的内镜治疗。本综述提供了食管支架在临床实践中的应用原理及局限性的关键要点和文献更新。

最新发现

食管支架置入的适应证可分为两组。第一组包括恶性或良性吞咽困难患者,食管支架可恢复管腔通畅。在过去几年中,临时支架置入越来越多地用于难治性良性食管狭窄的治疗管理。当内镜下反复探条扩张和其他内镜治疗方式失败时,可考虑置入食管支架。根据文献,全覆膜自膨式金属支架可能是治疗恶性和良性吞咽困难的首选。第二组包括食管腔向周围组织渗漏的患者。食管渗漏可分为三种形式,良性食管穿孔(医源性和自发性)、食管重建手术后吻合口漏以及瘘。在经过精心挑选的患者组中,可使用覆膜食管支架封闭渗漏,从而防止缺损周围组织进一步污染。在过去几年中,已经开发了几种经过验证的预测工具,可协助临床医生选择适合置入食管支架的患者。根据回顾性研究和专家意见,部分或全覆膜自膨式金属支架可能在食管渗漏治疗中发挥作用。目前的研究支持使用食管支架治疗恶性或良性吞咽困难以及食管渗漏。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98ae/5932108/c8428c65bd3a/11938_2018_181_Fig1_HTML.jpg

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