抗坏血酸和亚硫酸氢钠对肠道病毒的灭活作用
Inactivation of enteroviruses by ascorbic acid and sodium bisulfite.
作者信息
Salo R J, Cliver D O
出版信息
Appl Environ Microbiol. 1978 Jul;36(1):68-75. doi: 10.1128/aem.36.1.68-75.1978.
Abstract
Poliovirus type 1, coxsackievirus type A9, and echovirus type 7 were inactivated by sodium bisulfite and ascorbic acid. Inactivation rates depended upon concentration, temperature, and pH. RNA infectivity was lost during inactivation; the capsid was also altered by these inactivating agents, as determined by enzyme sensitivity assays and by tests of adsorption to cells. Structural modifications of the virus particles were not identical, suggesting that the mechanism of inactivation by ascorbic acid differs from that of sodium bisulfite.
摘要
1型脊髓灰质炎病毒、A9型柯萨奇病毒和7型埃可病毒可被亚硫酸氢钠和抗坏血酸灭活。灭活率取决于浓度、温度和pH值。在灭活过程中RNA感染力丧失；通过酶敏感性测定和细胞吸附试验确定，衣壳也被这些灭活剂改变。病毒颗粒的结构修饰并不相同，这表明抗坏血酸的灭活机制与亚硫酸氢钠不同。
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本文引用的文献
1
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Bacteriol Rev. 1964 Mar;28(1):2-13. doi: 10.1128/br.28.1.2-13.1964.
2
Fragments generated by pH dissociation of ME-virus and their relation to the structure of the virion.ME病毒pH解离产生的片段及其与病毒粒子结构的关系。
J Mol Biol. 1971 May 28;58(1):217-35. doi: 10.1016/0022-2836(71)90242-7.
3
Economical tissue culture technics.
Health Lab Sci. 1969 Jan;6(1):5-17.
4
Rapid method to determine labeling specificity of radioactive enteroviruses.放射性肠道病毒标记特异性的快速测定方法。
Appl Microbiol. 1973 Feb;25(2):313-4. doi: 10.1128/am.25.2.313-314.1973.
5
Interactions of components of human rhinovirus type 2 with Hela cells.人鼻病毒2型的组分与HeLa细胞的相互作用。
Virology. 1973 Feb;51(2):270-8. doi: 10.1016/0042-6822(73)90427-3.
6
Specific alterations of coxsackievirus B3 eluted from HeLa cells.从HeLa细胞中洗脱的柯萨奇病毒B3的特异性改变。
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