van Teeffelen Sven, Renner Lars D
Department of Microbiology, Institut Pasteur, 75724 Paris Cedex 15, France.
Leibniz Institute of Polymer Research and the Max Bergmann Center of Biomaterials, 01069 Dresden, Germany.
F1000Res. 2018 Feb 28;7:241. doi: 10.12688/f1000research.12663.1. eCollection 2018.
Cell shape and cell volume are important for many bacterial functions. In recent years, we have seen a range of experimental and theoretical work that led to a better understanding of the determinants of cell shape and size. The roles of different molecular machineries for cell-wall expansion have been detailed and partially redefined, mechanical forces have been shown to influence cell shape, and new connections between metabolism and cell shape have been proposed. Yet the fundamental determinants of the different cellular dimensions remain to be identified. Here, we highlight some of the recent developments and focus on the determinants of rod-like cell shape and size in the well-studied model organisms and .
细胞形状和细胞体积对许多细菌功能都很重要。近年来，我们看到了一系列实验和理论研究工作，这些工作使我们对细胞形状和大小的决定因素有了更好的理解。不同分子机制在细胞壁扩张中的作用已得到详细阐述并部分重新定义，机械力已被证明会影响细胞形状，并且有人提出了新陈代谢与细胞形状之间的新联系。然而，不同细胞维度的基本决定因素仍有待确定。在这里，我们重点介绍一些最新进展，并聚焦于在经过充分研究的模式生物和中杆状细胞形状和大小的决定因素。
