a Department of Physiotherapy , Monash University , Frankston , Australia.
Disabil Rehabil. 2019 Aug;41(17):2006-2014. doi: 10.1080/09638288.2018.1453875. Epub 2018 Mar 21.
Restless legs syndrome (RLS) is a sensorimotor disorder characterised by an uncomfortable urge to move the legs. Management is primarily pharmacological. Effects for non-pharmacological, non-surgical options are published but lack systematic examination. To synthesise results of non-pharmacological/non-surgical treatment compared to no-treatment controls or alternative treatment for RLS on any relevant outcome. Databases and reference lists of reviews were searched for randomised controlled trials (RCTs) comparing non-pharmacological treatment to alternative or no treatment controls for idiopathic RLS. Search results were independently screened for inclusion by two researchers; disagreements regarding eligibility were resolved with discussion. Outcomes were summarised, and pooled where possible in meta-analysis. The search yielded 442 articles. Eleven trials met inclusion criteria. Repetitive transcranial magnetic stimulation, exercise, compression devices, counterstrain manipulation, infrared therapy, and standard acupuncture were significantly more effective for RLS severity than control conditions. Vibration pads, cryotherapy, and transcranial direct current stimulation were ineffective in reducing RLS severity. Vibration pads, cryotherapy, yoga, compression devices, and acupuncture significantly improved some sleep-related outcomes. Few studies were identified and quality of evidence was not high. Some non-pharmacological interventions may be beneficial for reducing RLS severity and enhancing sleep. Implications for Rehabilitation The current management of restless leg syndrome is primarily pharmacological, and medications can have unwanted side effects. Repetitive transcranial magnetic stimulation, exercise, compression devices, counterstrain manipulation, infrared therapy, and standard acupuncture may reduce restless leg syndrome severity. Vibration pads, cryotherapy, yoga, compression devices, and acupuncture may improve some sleep-related outcomes in restless leg syndrome. Non-pharmacological interventions for RLS may cause placebo effects and rehabilitation professionals should control for this possibility in future investigations.
不宁腿综合征(RLS)是一种感觉运动障碍,其特征是腿部有不舒服的移动冲动。管理主要是药理学的。非药物、非手术选择的效果已经公布,但缺乏系统的检查。 综合比较非药物/非手术治疗与 RLS 任何相关结局的无治疗对照或替代治疗的结果。 数据库和综述的参考文献列表中搜索了比较非药物治疗与替代或无治疗对照的随机对照试验(RCT),用于治疗特发性 RLS。由两名研究人员独立筛选纳入研究;对于纳入标准的分歧,通过讨论解决。总结结果,并在可能的情况下进行荟萃分析。 搜索结果产生了 442 篇文章。11 项试验符合纳入标准。重复经颅磁刺激、运动、压缩装置、反向应变手法、红外治疗和标准针灸治疗对 RLS 严重程度的疗效明显优于对照组。振动垫、冷冻疗法和经颅直流电刺激对减轻 RLS 严重程度无效。振动垫、冷冻疗法、瑜伽、压缩装置和针灸显著改善了一些与睡眠相关的结果。 研究数量较少,证据质量不高。一些非药物干预可能有助于减轻 RLS 严重程度和改善睡眠。 康复意义 当前对不宁腿综合征的治疗主要是药物治疗,而药物可能会产生不良的副作用。重复经颅磁刺激、运动、压缩装置、反向应变手法、红外治疗和标准针灸可能会减轻不宁腿综合征的严重程度。振动垫、冷冻疗法、瑜伽、压缩装置和针灸可能会改善不宁腿综合征的一些睡眠相关结果。不宁腿综合征的非药物干预可能会产生安慰剂效应,康复专业人员在未来的研究中应控制这种可能性。