Carey Clifton M, Brown William
School of Dental Medicine, University of Colorado, 12800 E. 19th Ave., MS8310, Aurora, CO 80045, USA.
Dent J (Basel). 2017 Oct 6;5(4):27. doi: 10.3390/dj5040027.
The aging population experiences more gingival recession and root exposure which increases the opportunity for dentin erosion. This study tested the use of transverse microradiography (TMR) methods to assess dentin erosion and the interaction between fluoride and citric acid on the amount of erosion in the dentin samples. In a 4 × 3 interaction experimental design, four fluoride concentrations (0.00, 25.0, 50.0, and 100.0 mg/L) and three citric acid concentrations (0.0, 0.25, and 1.00%) were combined to form 12 experimental solutions. Forty-eight dentin samples were placed in the experimental solutions for 1 and 4 h and the amount of surface lost was determined by TMR methods. The resolution of the TMR method was 0.9 μm per pixel with a 0.1% and a 5% confidence interval of ±4.2 μm. Dentin erosion increased with the concentration of citric acid and time, the erosion decreased when concentration of fluoride was increased. Effects due to fluoride and citric acid concentrations individually, and their interaction on the amount of erosion observed was statistically significant (p < 0.0001). This study found that TMR methods are appropriate and that 25.0 mg/L was the optimal fluoride concentration to protect dentin from a 1.00% citric acid challenge.
老年人群牙龈退缩和牙根暴露更为常见，这增加了牙本质侵蚀的几率。本研究测试了横向微射线照相术（TMR）方法在评估牙本质侵蚀以及氟化物与柠檬酸对牙本质样本侵蚀量的相互作用方面的应用。在一个4×3的交互实验设计中，将四种氟化物浓度（0.00、25.0、50.0和100.0mg/L）与三种柠檬酸浓度（0.0、0.25和1.00%）组合，形成12种实验溶液。将48个牙本质样本置于实验溶液中1小时和4小时，通过TMR方法测定表面损失量。TMR方法的分辨率为每像素0.9μm，置信区间为0.1%和5%时为±4.2μm。牙本质侵蚀随柠檬酸浓度和时间增加而增加，氟化物浓度增加时侵蚀减少。氟化物和柠檬酸浓度各自以及它们对观察到的侵蚀量的相互作用的影响具有统计学意义（p<0.0001）。本研究发现，TMR方法是合适的，25.0mg/L是保护牙本质免受1.00%柠檬酸侵蚀的最佳氟化物浓度。
