Maruma Frans, Dlova Ncoza, Mofokeng Thabiso Rafaki Petrus, Al-Niaimi Firas
School of Clinical Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
J Cosmet Dermatol. 2025 Feb;24(2):e16729. doi: 10.1111/jocd.16729. Epub 2024 Dec 12.
We aimed to document the treatment outcomes of African patients treated with low-intensity electrodesiccation for DPN's. Other treatment options for DPN's include snip excision, light curettage, cryotherapy, and lasers devices such as PDL, Nd: YAG, KTP, and CO2, which are generally unsafe for darker skin types and come with high costs.
Nonprobability convenience sampling of patient records was used to extract retrospective data on demographics and treatment outcomes according to the inclusion criteria. The retrospective data analysis included chi-squared tests for associations, Kaplan-Meier survival analysis, and logistic regression analysis to examine relationships between dependent and independent variables.
A total of 137 patients were included in the study, with the majority being female (n = 129; 94.16%) compared with their male counterparts (n = 8; 5.84%). Most patients were under 40 years of age (n = 74; 54.00%), whereas the remaining were above 40 years of age (n = 63; 46.00%). The majority of patients had Fitzpatrick skin type V (n = 99; 72.26%). Adverse events such as milia (n = 4) and scarring (n = 2) were observed, but these were not associated with age, sex, or survival rate (p value > 0.05).
The study was conducted at a single center, which limits the ability to generalize the results.
The low-intensity electrodesiccation technique was found to be a safe and cost-effective method for treating DPN's in African patients.
我们旨在记录采用低强度电干燥法治疗皮肤乳头瘤状营养不良（DPN）的非洲患者的治疗结果。DPN的其他治疗选择包括剪除切除术、轻度刮除术、冷冻疗法以及诸如脉冲染料激光（PDL）、钕钇铝石榴石激光（Nd:YAG）、磷酸钛氧钾激光（KTP）和二氧化碳激光等激光设备，这些方法通常对肤色较深的皮肤类型不安全且成本高昂。
采用非概率方便抽样法从患者记录中提取符合纳入标准的人口统计学和治疗结果的回顾性数据。回顾性数据分析包括用于关联性分析的卡方检验、Kaplan-Meier生存分析以及用于检验因变量和自变量之间关系的逻辑回归分析。
该研究共纳入137例患者，其中女性居多（n = 129；94.16%），男性较少（n = 8；5.84%）。大多数患者年龄在40岁以下（n = 74；54.00%），其余患者年龄在40岁以上（n = 63；46.00%）。大多数患者的皮肤类型为Fitzpatrick V型（n = 99；72.26%）。观察到了粟丘疹（n = 4）和瘢痕形成（n = 2）等不良事件，但这些与年龄、性别或生存率无关（p值>0.05）。
该研究在单一中心进行，这限制了结果的推广能力。
低强度电干燥技术被发现是治疗非洲患者DPN的一种安全且具有成本效益的方法。
