Dutheil Cyril, Korobelnik Jean-François, Delyfer Marie-Noëlle, Rougier Marie-Bénédicte
1 Department of Ophthalmology, Bordeaux University Hospital, Amélie Raba-Léon, Bordeaux, France.
2 Team LEHA, Bordeaux Population Health Research Center-U1219, INSERM, Bordeaux, France.
Eur J Ophthalmol. 2018 Sep;28(5):614-621. doi: 10.1177/1120672118759623. Epub 2018 Mar 23.
To analyze the ability of optical coherence tomography angiography to identify choroidal neovascularization in multifocal choroiditis and to describe active and inactive choroidal neovascularization findings.
Retrospective study of consecutive patients with multifocal choroiditis and choroidal neovascularization examined between January and November 2016. In addition to usual exams, optical coherence tomography angiography (AngioPlex™ CIRRUS™ HD-OCT model 5000; Carl Zeiss Meditec, Inc., Dublin, CA, USA) images were assessed for morphological analysis: choroidal neovascularization size, choroidal neovascularization margin (well or poorly circumscribed), choroidal neovascularization shape (tangled or interlacing), choroidal neovascularization core (feeder vessel) and dark ring around the choroidal neovascularization.
A total of 10 eyes were included. Optical coherence tomography angiography identified all choroidal neovascularization. Active choroidal neovascularization had well-circumscribed margins (67%), interlacing shape (83%), and a surrounding dark ring (83%). Inactive choroidal neovascularization had rather poorly circumscribed margins (75%), tangled shape, and "dead tree" appearance (50%) with less frequently a surrounding dark ring (50%).
Optical coherence tomography angiography is adapted to confirm the diagnosis of choroidal neovascularization complicating multifocal choroiditis, but it is still insufficient to differentiate active and inactive lesions.
分析光学相干断层扫描血管造影术识别多灶性脉络膜炎中脉络膜新生血管的能力，并描述活动性和非活动性脉络膜新生血管的表现。
对2016年1月至11月间连续检查的多灶性脉络膜炎合并脉络膜新生血管患者进行回顾性研究。除常规检查外，对光学相干断层扫描血管造影（AngioPlex™ CIRRUS™ HD-OCT 5000型；美国加利福尼亚州都柏林市卡尔蔡司医疗技术公司）图像进行形态学分析：脉络膜新生血管大小、脉络膜新生血管边缘（边界清晰或不清晰）、脉络膜新生血管形状（缠结或交织）、脉络膜新生血管核心（供血血管）以及脉络膜新生血管周围的暗环。
共纳入10只眼。光学相干断层扫描血管造影术识别出所有脉络膜新生血管。活动性脉络膜新生血管边缘边界清晰（67%）、形状交织（83%），且有周围暗环（83%）。非活动性脉络膜新生血管边缘边界大多不清晰（75%）、形状缠结，呈“枯树”样表现（50%），周围暗环较少见（50%）。
光学相干断层扫描血管造影术适用于确诊多灶性脉络膜炎合并的脉络膜新生血管，但在区分活动性和非活动性病变方面仍不足。
