Sabanci University Nanotechnology Research and Application Center, Orta Mahalle, 34956 Tuzla, Istanbul, Turkey.
Department of Biosciences and Biotechnology, Banasthali University, Rajasthan 304022, India.
Biosensors (Basel). 2018 Mar 23;8(2):28. doi: 10.3390/bios8020028.
Food and environmental monitoring is one of the most important aspects of dealing with recent threats to human well-being and ecosystems. In this framework, electrochemical aptamer-based sensors are resilient due to their ability to resolve food and environmental contamination. An aptamer-based sensor is a compact analytical device combining an aptamer as the bio-sensing element integrated on the transducer surface. Aptamers display many advantages as biorecognition elements in sensor development when compared to affinity-based (antibodies) sensors. Aptasensors are small, chemically unchanging, and inexpensive. Moreover, they offer extraordinary elasticity and expediency in the design of their assemblies, which has led to innovative sensors that show tremendous sensitivity and selectivity. This review will emphasize recent food and environmental safeguarding using aptasensors; there are good prospects for their performance as a supplement to classical techniques.
食品与环境监测是应对人类福祉和生态系统当前面临威胁的最重要措施之一。在此背景下，基于电化学适配体的传感器具有较强的环境适应能力，在解决食品和环境污染问题方面发挥了重要作用。基于适配体的传感器是一种将适配体作为生物传感元件集成在换能器表面的紧凑型分析设备。与基于亲和力的（抗体）传感器相比，适配体作为生物识别元件在传感器开发中具有许多优势。适配体传感器具有体积小、化学性质稳定和价格低廉等优点。此外，它们在组件设计方面具有非凡的灵活性和便利性，这使得新型传感器具有极高的灵敏度和选择性。本综述将重点介绍基于适配体的传感器在食品和环境安全保障方面的最新应用，它们有望成为经典技术的补充手段。
