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Computational modeling suggests distinct, location-specific function of norepinephrine in olfactory bulb and piriform cortex.计算模型表明去甲肾上腺素在嗅球和梨状皮质中具有独特的、特定位置的功能。
Front Comput Neurosci. 2015 Jun 16;9:73. doi: 10.3389/fncom.2015.00073. eCollection 2015.
2
Odor Memory and Discrimination Covary as a Function of Delay between Encoding and Recall in Rats.气味记忆与辨别能力随大鼠编码与回忆之间延迟的变化而共同变化。
Chem Senses. 2015 Jun;40(5):315-23. doi: 10.1093/chemse/bjv013. Epub 2015 Apr 21.
3
Stressors impair odor recognition memory via an olfactory bulb-dependent noradrenergic mechanism.应激源通过依赖嗅球的去甲肾上腺素能机制损害嗅觉识别记忆。
Front Integr Neurosci. 2013 Dec 23;7:97. doi: 10.3389/fnint.2013.00097. eCollection 2013.
4
Duration and specificity of olfactory nonassociative memory.嗅觉非联想记忆的持续时间和特异性。
Chem Senses. 2013 May;38(4):369-75. doi: 10.1093/chemse/bjt010. Epub 2013 Mar 18.
5
Noradrenergic but not cholinergic modulation of olfactory bulb during processing of near threshold concentration stimuli.在近阈值浓度刺激处理过程中,去甲肾上腺素能而非胆碱能对嗅球的调节作用。
Behav Neurosci. 2012 Oct;126(5):720-8. doi: 10.1037/a0030006.
6
Action of the noradrenergic system on adult-born cells is required for olfactory learning in mice.去甲肾上腺素能系统对成年新生细胞的作用是小鼠嗅觉学习所必需的。
J Neurosci. 2012 Mar 14;32(11):3748-58. doi: 10.1523/JNEUROSCI.6335-11.2012.
7
Nonlinear effects of noradrenergic modulation of olfactory bulb function in adult rodents.去甲肾上腺素对成年啮齿动物嗅球功能的调制的非线性影响。
J Neurophysiol. 2011 Apr;105(4):1432-43. doi: 10.1152/jn.00960.2010. Epub 2011 Jan 27.
8
Noradrenergic modulation of behavioral odor detection and discrimination thresholds in the olfactory bulb.去甲肾上腺素对嗅球行为气味检测和辨别阈值的调制作用。
Eur J Neurosci. 2010 Aug;32(3):458-68. doi: 10.1111/j.1460-9568.2010.07297.x. Epub 2010 Jul 5.
9
Activation of alpha1 and alpha2 noradrenergic receptors exert opposing effects on excitability of main olfactory bulb granule cells.α1 和 α2 去甲肾上腺素受体的激活对嗅球颗粒细胞的兴奋性产生相反的影响。
Neuroscience. 2010 Aug 25;169(2):882-92. doi: 10.1016/j.neuroscience.2010.05.010. Epub 2010 May 11.
10
Early transformations in odor representation.气味表征的早期转变。
Trends Neurosci. 2010 Mar;33(3):130-9. doi: 10.1016/j.tins.2009.12.004. Epub 2010 Jan 8.

去甲肾上腺素对嗅觉感知和学习的影响。

Noradrenergic effects on olfactory perception and learning.

机构信息

Computational Physiology Lab, Department of Neurobiology and Behavior, Cornell University, Ithaca NY 14850, United States.

Department of Psychology, Binghamton University, 4400 Vestal Parkway East, Binghamton, NY 13902-6000, United States.

出版信息

Brain Res. 2019 Apr 15;1709:33-38. doi: 10.1016/j.brainres.2018.03.021. Epub 2018 Mar 21.

DOI:10.1016/j.brainres.2018.03.021
PMID:29574010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6150838/
Abstract

We here review modulation of olfactory guided behavioral tasks by noradrenaline. In this review we focus on modulation of the main olfactory system in adult rodents. We detail behavioral paradigms commonly used and discuss how sensory perception and learning can be measured using these paradigms. We then describe neuromodulatory effects on several aspects of olfactory processing, including detection and encoding. We describe how memory duration, specificity and duration are affected by noradrenergic modulation.

摘要

我们在此回顾去甲肾上腺素对嗅觉导向行为任务的调制。在本综述中,我们专注于成年啮齿动物主要嗅觉系统的调制。我们详细介绍了常用的行为范式,并讨论了如何使用这些范式来测量感觉感知和学习。然后,我们描述了神经调制对嗅觉处理的几个方面的影响,包括检测和编码。我们描述了去甲肾上腺素调制如何影响记忆的持续时间、特异性和时长。