Synzynys B I, Aminev A G, Konstantinova S A, Saenko A S
Radiobiologiia. 1987 Jul-Aug;27(4):459-62.
Cells of a suspension HeLa culture at the logarithmic phase of growth were exposed to 60Co-gamma-rays (5 Gy), incubated in the nutritious medium, and in 4 h subjected to repeated irradiation: the dose-response function and the dynamics of DNA synthesis inhibition were determined. It was shown that DNA synthesis was inhibited to a lesser extent after preirradiation, in other words, DNA synthesis was radioresistant. A correlation between this synthesis and reproductive cell death is discussed.
处于对数生长期的悬浮培养海拉细胞,经60Co-γ射线(5 Gy)照射后,在营养培养基中孵育,并在4小时后进行重复照射:测定了剂量反应函数和DNA合成抑制的动力学。结果表明,预照射后DNA合成的抑制程度较小,换句话说,DNA合成具有抗辐射性。本文讨论了这种合成与生殖细胞死亡之间的相关性。