Trompler A T, Sold G, Figulla H R, Luig H, Kreuzer H
Z Kardiol. 1987 Jun;76(6):346-50.
To prove the use of Doppler-echocardiography in the determination of cardiac output during supine bicycle exercise, 14 patients suffering from dilatative cardiomyopathy were studied. Cardiac output was simultaneously determined by Doppler-echocardiography and with radionuclide ventriculography. In some cases, cardiac output was additionally measured using the thermodilution technique. In 12 patients (success rate 86%) flow velocity signals from the ascending aorta could be recorded with sufficient quality. Both methods were closely correlated, the r-value was 0.91 and the standard error of estimate was found to be 2.09 l/min. Mean deviation was 1.50 l/min (0.09-5.45 l/min) or 13% (1%-64%) respectively. For changes in cardiac output with exercise, the correlation was r = 0.88 with a mean deviation of 69% (2%-453%). The coefficient of variation for exercise measurements was 19% and did not differ from the resting value of 20%. Comparing the mean values of the whole group, no differences between the two methods could be found at rest, during exercise or for changes from rest to maximal exercise. Using the suprasternal approach, aortic flow velocities can be assessed by Doppler-echocardiography during exercise. Gross estimation of cardiac output during exercise seems possible; judgement of changes in cardiac output in individual cases appears to be uncertain.
为证明多普勒超声心动图在测定仰卧位自行车运动时心输出量中的应用,对14例扩张型心肌病患者进行了研究。通过多普勒超声心动图和放射性核素心室造影同时测定心输出量。在某些情况下,还使用热稀释技术测量心输出量。12例患者(成功率86%)能够以足够的质量记录升主动脉的血流速度信号。两种方法密切相关,r值为0.91,估计标准误差为2.09升/分钟。平均偏差分别为1.50升/分钟(0.09 - 5.45升/分钟)或13%(1% - 64%)。对于运动时心输出量的变化,相关性为r = 0.88,平均偏差为69%(2% - 453%)。运动测量的变异系数为19%,与静息值20%无差异。比较整个组的平均值,在静息、运动期间或从静息到最大运动的变化中,两种方法均未发现差异。使用胸骨上窝方法,运动期间可通过多普勒超声心动图评估主动脉血流速度。运动时心输出量的大致估计似乎可行;但个别病例中心输出量变化的判断似乎不确定。