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美国妇产科医师学会委员会意见 No.732:妊娠期流感疫苗接种。

ACOG Committee Opinion No. 732: Influenza Vaccination During Pregnancy.

出版信息

Obstet Gynecol. 2018 Apr;131(4):e109-e114. doi: 10.1097/AOG.0000000000002588.

Abstract

Influenza vaccination is an essential element of prepregnancy, prenatal, and postpartum care because influenza can result in serious illness, including a higher chance of progressing to pneumonia, when it occurs during the antepartum or postpartum period. In addition to hospitalization, pregnant women with influenza are at increased risk of intensive care unit admission and adverse perinatal and neonatal outcomes. The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices and the American College of Obstetricians and Gynecologists recommend that all adults receive an annual influenza vaccine and that women who are or will be pregnant during influenza season receive an inactivated influenza vaccine as soon as it is available. In the United States, the influenza season typically occurs from October to May. Ideally, an influenza vaccination should be given before the end of October, but vaccination throughout the influenza season is encouraged to ensure protection during the period of circulation. Any of the licensed, recommended, age-appropriate, inactivated influenza vaccines can be given safely during any trimester. Therefore, it is critically important that obstetrician-gynecologists and other obstetric care providers recommend and advocate for the influenza vaccine. Obstetrician-gynecologists are encouraged to stock and administer the influenza vaccine to their pregnant patients in their offices, and should get the influenza vaccine themselves every season. If the influenza vaccine cannot be offered in a practice, obstetrician-gynecologists and obstetric care providers should refer patients to another health care provider, pharmacy, or community vaccination center. This updated Committee Opinion includes more recent data on the safety and efficacy of influenza vaccination during pregnancy and recommendations for treatment and postexposure chemoprophylaxis.

摘要

流感疫苗接种是备孕、产前和产后护理的重要组成部分,因为流感在产前或产后期间发生时可能导致严重疾病,包括肺炎的几率增加。除住院治疗外,患有流感的孕妇更有可能入住重症监护病房,并且围产期和新生儿结局不良的风险增加。疾病预防控制中心免疫实践咨询委员会和美国妇产科医师学会建议所有成年人每年接种流感疫苗,并且在流感季节期间或将要怀孕的妇女应尽快接种灭活流感疫苗。在美国,流感季节通常从 10 月持续到 5 月。理想情况下,流感疫苗应在 10 月底之前接种,但整个流感季节都鼓励接种疫苗,以确保在流行期间得到保护。任何获得许可、推荐、适合年龄的灭活流感疫苗都可以在任何孕期安全接种。因此,妇产科医生和其他产科护理提供者建议并倡导接种流感疫苗非常重要。鼓励妇产科医生在其办公室为孕妇储备和接种流感疫苗,并在每个季节都接种流感疫苗。如果无法在实践中提供流感疫苗,妇产科医生和产科护理提供者应将患者转介给其他医疗保健提供者、药房或社区疫苗接种中心。本更新的委员会意见包括最近关于妊娠期流感疫苗接种的安全性和有效性的数据,以及治疗和暴露后化学预防的建议。

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