Surkar Swati M, Hoffman Rashelle M, Willett Sandra, Flegle Janice, Harbourne Regina, Kurz Max J
Department of Physical Therapy (Drs Surkar, Hoffman, and Kurz and Ms Willett) and Department of Occupational Therapy (Ms Flegle), Munroe Meyer Institute of Genetics and Rehabilitation, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, Nebraska; Department of Physical Therapy (Dr Harbourne), John G. Rangos School of Health Sciences, Duquesne University, Pittsburgh, Pennsylvania.
Pediatr Phys Ther. 2018 Apr;30(2):93-100. doi: 10.1097/PEP.0000000000000486.
To determine the changes in the prefrontal cortical (PFC) activation following hand-arm bimanual intensive therapy (HABIT) in children with hemiplegic cerebral palsy (HCP).
Nine children with HCP and 15 children who were developing typically participated in the study. Children with HCP received 50 hours of HABIT. We assessed pre- and post-HABIT PFC activation using functional near-infrared spectroscopy neuroimaging. Bimanual coordination and motor task performance were assessed using the Assisting Hand Assessment (AHA), the average number of shapes matched, the shape matching errors, the reaction time, the 9-hole peg test, and the box and blocks test.
The PFC activation decreased following HABIT and became similar to what was seen in the children who were developing typically. Post-HABIT PFC activation improvements paralleled with the improvements seen in the AHA and the behavioral outcomes.
HABIT potentially improves the PFC's involvement in the action planning of the upper extremity movements in children with HCP.
确定偏瘫型脑瘫（HCP）患儿接受手臂双手强化治疗（HABIT）后前额叶皮质（PFC）激活的变化。
9名HCP患儿和15名发育正常的儿童参与了该研究。HCP患儿接受了50小时的HABIT治疗。我们使用功能性近红外光谱神经成像评估了HABIT治疗前后的PFC激活情况。使用辅助手评估（AHA）、匹配形状的平均数量、形状匹配错误、反应时间、9孔插板测试和箱块测试评估双手协调性和运动任务表现。
HABIT治疗后PFC激活减少，变得与发育正常儿童的情况相似。HABIT治疗后PFC激活的改善与AHA及行为结果的改善平行。
HABIT可能改善PFC对HCP患儿上肢运动动作规划的参与。
