Department of International Healthcare Administration, Daegu Catholic University, Kyungbuk 38430, Korea.
College of Pharmacy, Keimyung University, Daegu 42601, Korea.
Int J Environ Res Public Health. 2018 Mar 25;15(4):589. doi: 10.3390/ijerph15040589.
Humans are exposed to the environmental pollutants 2,4-dichlorophenol (2,4-DCP) and 2,5-dichlorophenol (2,5-DCP) through air, the use of water and the consumption of products. In this study, we evaluated the urinary concentrations of these compounds in Korean people between the ages of 18 to 69 years, by making use of data from the Korean National Human Biomonitoring Survey that was completed in 2009. Of 1865 representative Koreans, 63.4% and 97.9% were found to have concentrations of 2,4-DCP and 2,5-DCP > 0.05 μg/L (limit of detection) in their urine, respectively. The geometric mean of urinary concentrations was 0.14 μg/L (confidence interval of 95% = 0.13-0.16) and 0.44 μg/L (confidence interval = 0.41-0.48), respectively. It was found that the adjusted proportional changes in 2,4-DCP concentrations were significantly associated with body mass index, whereas those of 2,5-DCP concentrations were influenced by place of residence. From these findings, it is evident that most adults in Korea have levels of 2,4-DCP and 2,5-DCP that are detectable in their urine and the burden of these compounds on their bodies varies depending on numerous demographic factors.
人类通过空气、水的使用和产品的消费接触到环境污染物 2,4-二氯苯酚（2,4-DCP）和 2,5-二氯苯酚（2,5-DCP）。在这项研究中，我们利用韩国于 2009 年完成的全国人类生物监测调查的数据，评估了 18 至 69 岁韩国人的尿液中这些化合物的浓度。在 1865 名有代表性的韩国人中，分别有 63.4%和 97.9%的人的尿液中 2,4-DCP 和 2,5-DCP 的浓度>0.05μg/L（检测限）。尿液中浓度的几何平均值分别为 0.14μg/L（95%置信区间=0.13-0.16）和 0.44μg/L（置信区间=0.41-0.48）。结果发现，2,4-DCP 浓度的调整后比例变化与体重指数显著相关，而 2,5-DCP 浓度则受居住地点的影响。从这些发现可以看出，韩国大多数成年人的尿液中都能检测到 2,4-DCP 和 2,5-DCP，而且这些化合物对他们身体的负担因众多人口统计学因素而异。
