Jiang Gening, Chen Chang, Zhu Yuming, Xie Dong, Dai Jie, Jin Kaiqi, Shen Yingran, Wang Haifeng, Li Hui, Zhang Lanjun, Gao Shugeng, Chen Keneng, Zhang Lei, Zhou Xiao, Shi Jingyun, Wang Hao, Xie Boxiong, Jiang Lei, Fan Jiang, Zhao Deping, Chen Qiankun, Duan Liang, He Wenxin, Zhou Yiming, Liu Hongcheng, Zhao Xiaogang, Zhang Peng, Qin Xiong
Tongji University affiliated Shanghai Pulmonary Hospital, Shanghai 200043 , China.
Capital Medical University Affiliated Beijing Chao-Yang Hospital, Beijing 100020 , China.
Zhongguo Fei Ai Za Zhi. 2018 Mar 20;21(3):147-159. doi: 10.3779/j.issn.1009-3419.2018.03.05.
Background and objective As computed tomography (CT) screening for lung cancer becomes more common in China, so too does detection of pulmonary ground-glass nodules (GGNs). Although anumber of national or international guidelines about pulmonary GGNs have been published,most of these guidelines are produced by respiratory, oncology or radiology physicians, who might not fully understand the progress of modern minimal invasive thoracic surgery, and these current guidelines may overlook or underestimate the value of thoracic surgery in the management of pulmonary GGNs. In addition, the management for pre-invasive adenocarcinoma is still controversial. Based onthe available literature and experience from Shanghai Pulmonary Hospital, we composed this consensus about diagnosis and treatment of pulmonary GGNs. For lesions which are considered as adenocarcinoma in situ, chest thin layer CT scan follow-up is recommended and resection can only be adopt in some specific cases and excision should not exceed single segment resection. For lesions which are considered as minimal invasive adenocarcinoma, limited pulmonary resection or lobectomy is recommended. For lesions which are considered as early stage invasive adenocarcinoma, pulmonary resection is recommend and optimal surgical methods depend on whether ground glass component exist, location, volume and number of the lesions and physical status of patients. Principle of management of multiple pulmonary nodules is that primary lesions should be handled with priority, with secondary lesions taking into account. .
背景与目的 随着计算机断层扫描(CT)肺癌筛查在中国日益普遍,肺磨玻璃结节(GGN)的检出率也随之增加。尽管已经发布了一些关于肺GGN的国家或国际指南,但这些指南大多由呼吸科、肿瘤科或放射科医生制定,他们可能并不完全了解现代微创胸外科的进展,而且这些现行指南可能会忽视或低估胸外科在肺GGN治疗中的价值。此外,对原位腺癌的治疗仍存在争议。基于现有文献以及上海肺科医院的经验,我们撰写了这份关于肺GGN诊断和治疗的共识。对于被认为是原位腺癌的病变,建议进行胸部薄层CT扫描随访,仅在某些特定情况下可采用切除,且切除范围不应超过单肺段切除。对于被认为是微浸润腺癌的病变,建议进行肺叶局限性切除或肺叶切除术。对于被认为是早期浸润性腺癌的病变,建议进行肺切除,最佳手术方式取决于是否存在磨玻璃成分、病变的位置、体积和数量以及患者的身体状况。多个肺结节的处理原则是优先处理原发性病变,同时兼顾继发性病变。