Department of Molecular Cell Biology, Neurophysiology Unit, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands; International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Movement Disorders Unit and Division of Sleep Medicine, Massachusetts General Hospital, Harvard Medical School, 165 Cambridge Street, Suite 600, Boston, MA 02446, USA.
Trends Neurosci. 2018 May;41(5):252-254. doi: 10.1016/j.tins.2018.03.002. Epub 2018 Mar 24.
A growing body of work is investigating the safety and efficacy of light in Parkinson's disease (PD). Here we discuss the potential of this emerging therapy to improve both motor and non-motor symptoms of PD. We also highlight directions for future basic, translational, and clinical research that are critical for the development of mechanism-based protocols of light therapy in PD.
越来越多的研究正在探索光疗在帕金森病(PD)中的安全性和有效性。在这里,我们讨论了这种新兴疗法改善 PD 的运动和非运动症状的潜力。我们还强调了未来基础、转化和临床研究的方向,这些方向对于制定基于机制的 PD 光疗方案至关重要。