Maastricht University Medical Center, Dept of Respiratory Diseases, Maastricht, The Netherlands.
CIRO+, Centre of Expertise for Chronic Organ Failure, Horn, The Netherlands.
Eur Respir Rev. 2018 Mar 28;27(147). doi: 10.1183/16000617.0125-2017. Print 2018 Mar 31.
This review summarises ongoing developments in personalised medicine and individualised medicine in chronic obstructive pulmonary disease (COPD). Currently applied classification systems largely ignore the complexity and heterogeneity of the COPD syndrome. Personalised medicine has to consider the influence of unique circumstances of the person, which contribute to this heterogeneity and complexity. Pulmonary rehabilitation is described as a comprehensive, individualised intervention based on thorough assessment of identifiable treatable traits. Partnership in care will become a crucial factor to improve and maintain health. Tolerating uncertainty and unpredictability will enrich future doctor-patient relationships.
这篇综述总结了慢性阻塞性肺疾病（COPD）个体化医学和个体化医学的最新进展。目前应用的分类系统在很大程度上忽略了 COPD 综合征的复杂性和异质性。个体化医学必须考虑到导致这种异质性和复杂性的个体独特情况的影响。肺康复被描述为一种基于对可治疗特征进行全面评估的综合个体化干预。医患合作将成为改善和维持健康的关键因素。容忍不确定性和不可预测性将丰富未来的医患关系。
