Mañós-Pujol M, Buendia E, Mestre M, Jimenéz R, Gil E, Menén J P, Mañós-Gonzalbo M
Department of Otorhinolaryngology, Hospital de Bellvitge, University of Barcelona, Spain.
Clin Otolaryngol Allied Sci. 1987 Aug;12(4):283-7. doi: 10.1111/j.1365-2273.1987.tb00203.x.
Recurrent Bell's palsy is a rare form of facial paralysis. To investigate the role which cellular immunity plays in the aetiology of recurrent Bell's palsy, we evaluated a series of such patients using a laboratory test specially formulated to test the cellular immune system. We measured T-lymphocyte and T-lymphocyte subsets in the peripheral blood of 10 recurrent Bell's palsy patients and in 30 healthy volunteers. T-lymphocytes and T-lymphocyte subsets were reduced significantly in the patients, but the T-helper: T-cytotoxic ratio was normal. Cellular immunity abnormalities were therefore found in the peripheral blood of patients with recurrent Bell's palsy, supporting the concept that this is an immunomediated demyelinating disease.
复发性贝尔麻痹是一种罕见的面神经麻痹形式。为了研究细胞免疫在复发性贝尔麻痹病因学中所起的作用，我们使用专门设计用于检测细胞免疫系统的实验室检测方法，对一系列此类患者进行了评估。我们检测了10例复发性贝尔麻痹患者和30名健康志愿者外周血中的T淋巴细胞及其亚群。患者的T淋巴细胞及其亚群显著减少，但辅助性T细胞与细胞毒性T细胞的比例正常。因此，在复发性贝尔麻痹患者的外周血中发现了细胞免疫异常，这支持了该病是一种免疫介导的脱髓鞘疾病的观点。
