College of Chemistry and Chemical Engineering, Yantai University, Yantai, 264005, China.
Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, 264003, China.
Mikrochim Acta. 2018 Feb 10;185(3):166. doi: 10.1007/s00604-018-2712-y.
A nanohybrid electrode was prepared by functionalizing reduced graphene oxide nanosheets (GNs) with gold nanoparticles (AuNP), CoS, and an ionic liquid. It is shown to enable voltammetric determination of dopamine (DA). The AuNPs were electrodeposited onto the electrode that was first modified with CoS and the IL-GNs to obtain a well-defined 3-dimensional and porous structure. The nanohybrid material displays high catalytic activity and an ultrasensitive cyclic voltammetric response to DA. The peak current (best measured at a working voltage of 0.17 V vs. Ag/AgCl) increases linearly in the 0.1 to 400 μM DA concentration range, with a 40 nM detection limit (at S/N = 3). The electrode was successfully applied to the determination of DA in spiked serum samples. Graphical abstract Schematic of the preparation of a nanohybrid electrode odified with graphene oxide nanosheets functionalized with gold nanoparticles/CoS/ionic liquid by electrodeposition. The electrode exhibits excellent electrocatalytic performance with respect to the electrochemical detection of dopamine. The determination of the DPV curves provides satisfactory results which can be characterized by a linear response for DA concentrations ranging from 0.1 to 400.0 μM with a 40 nM detection limit (at S/N = 3).
一种纳米杂化电极是通过将金纳米粒子（AuNP）、CoS 和离子液体功能化还原氧化石墨烯纳米片（GNs）制备的。它被证明可以用于多巴胺（DA）的伏安法测定。首先将 CoS 和 IL-GNs 修饰到电极上，然后将 AuNPs 电沉积到电极上，以获得具有良好定义的 3 维多孔结构。该纳米杂化材料显示出对 DA 高的催化活性和超灵敏的循环伏安响应。在 0.1 至 400 μM DA 浓度范围内，峰电流（最佳在相对于 Ag/AgCl 的 0.17 V 工作电压下测量）呈线性增加，检测限为 40 nM（S/N=3）。该电极成功地应用于测定加标血清样品中的 DA。示意图说明通过电沉积在氧化石墨烯纳米片上功能化金纳米粒子/CoS/离子液体修饰纳米杂化电极的制备。该电极对多巴胺电化学检测具有优异的电催化性能。通过 DPV 曲线的测定可以得到令人满意的结果，其特征是 DA 浓度在 0.1 至 400.0 μM 范围内呈线性响应，检测限为 40 nM（S/N=3）。
