Sanz-Esteban Ismael, Calvo-Lobo Cesar, Ríos-Lago Marcos, Álvarez-Linera Juan, Muñoz-García Daniel, Rodríguez-Sanz David
European University, School of Sports Science, Madrid Department of Nursing and Physical Therapy, Institute of Biomedicine (IBIOMED), Universidad de León, Ponferrada, León Department of Psychology, Universidad Nacional de Educación a Distancia UNED Department of Neuroradiology, Ruber International Hospital Motion in Brains Research Group, Instituto de Neurociencias y Ciencias del Movimiento, Centro Superior de Estudios Universitarios La Salle, Universidad Autónoma de Madrid, Madrid, Spain.
Medicine (Baltimore). 2018 Mar;97(13):e0253. doi: 10.1097/MD.0000000000010253.
A century of research in human brain parcellation has demonstrated that different brain areas are associated with functional tasks. New neuroscientist perspectives to achieve the parcellation of the human brain have been developed to know the brain areas activation and its relationship with different stimuli. This descriptive study aimed to compare brain regions activation by specific tactile input (STI) stimuli according to the Vojta protocol (STI-group) to a non-STI stimulation (non-STI-group). An exploratory functional magnetic resonance imaging (fMRI) study was performed. The 2 groups of participants were passively stimulated by an expert physical therapist using the same paradigm structure, although differing in the place of stimulation. The stimulation was presented to participants using a block design in all cases. A sample of 16 healthy participants, 5 men and 11 women, with mean age 31.31 ± 8.13 years was recruited. Indeed, 12 participants were allocated in the STI-group and 4 participants in the non-STI-group. fMRI was used to map the human brain in vivo while these tactile stimuli were being applied. Data were analyzed using a general linear model in SPM12 implemented in MATLAB. Differences between groups showed a greater activation in the right cortical areas (temporal and frontal lobes), subcortical regions (thalamus, brainstem, and basal nuclei), and in the cerebellum (anterior lobe). STI-group had specific difference brain activation areas, such as the ipsilateral putamen. Future studies should study clinical implications in neurorehabilitation patients.
一个世纪以来对人类脑部分割的研究表明，不同的脑区与功能任务相关联。为了了解脑区激活情况及其与不同刺激的关系，已经开发出了实现人类脑部分割的新神经科学视角。这项描述性研究旨在比较根据沃伊塔方案进行特定触觉输入（STI）刺激的脑区激活情况（STI组）与非STI刺激（非STI组）。进行了一项探索性功能磁共振成像（fMRI）研究。两组参与者均由一名专业物理治疗师使用相同的范式结构进行被动刺激，只是刺激部位不同。在所有情况下，刺激均采用组块设计呈现给参与者。招募了16名健康参与者，其中5名男性和11名女性，平均年龄31.31±8.13岁。实际上，12名参与者被分配到STI组，4名参与者被分配到非STI组。在施加这些触觉刺激时，使用fMRI对活体人类大脑进行映射。使用MATLAB中实现的SPM12中的一般线性模型对数据进行分析。组间差异显示，右侧皮质区域（颞叶和额叶）、皮质下区域（丘脑、脑干和基底核）以及小脑（前叶）有更大的激活。STI组有特定的脑激活差异区域，如同侧壳核。未来的研究应该研究对神经康复患者的临床意义。
