Cho Yang K, Kwon Jin W, Konda Sneha, Ambati Balamurali K
Department of Ophthalmology, St. Vincent's Hospital College of Medicine, The Catholic University of Korea, Paldal-Gu, Suwon, Gyeonggi-Do, Korea.
College of Medicine, Texas A&M Health Sciences Center, Bryan, College Station, TX.
Cornea. 2018 Jun;37(6):755-759. doi: 10.1097/ICO.0000000000001592.
To evaluate the incidence, related perioperative factors, clinical characteristics, and possible etiologies of epithelial keratitis after cataract surgery.
A retrospective chart review of 666 eyes in 666 patients who underwent cataract surgery was performed to evaluate the incidence of epithelial keratitis and related factors in the postoperative period.
Postoperative epithelial keratitis developed in 15 eyes. Eleven of the 15 eyes were diagnosed with herpes simplex keratitis (HSK); 10 of the 11 eyes were diagnosed by polymerase chain reaction, and the remaining 1 eye by clinical diagnosis. All patients diagnosed with HSK had no previous clinical history of the infection before undergoing cataract surgery. Initially, the diagnosis of all 15 eyes was toxic keratitis, but the final diagnosis of 11 of the initial 15 was found to be epithelial herpes keratitis. The incision location was shown to be related to the occurrence of HSK in our study (P < 0.05).
HSK epithelial keratitis after cataract surgery is a relatively uncommon complication and can be misdiagnosed in its early disease course because of its relative rarity. This study explores the possibility that the temporal corneal penetrating incisional approach used in routine cataract surgery interrupts the corneal nerves and subsequently can trigger reactivation of HSK.
评估白内障手术后上皮性角膜炎的发生率、相关围手术期因素、临床特征及可能病因。
对666例接受白内障手术患者的666只眼进行回顾性病历审查,以评估术后上皮性角膜炎的发生率及相关因素。
15只眼发生了术后上皮性角膜炎。15只眼中11只被诊断为单纯疱疹病毒性角膜炎(HSK);11只眼中10只通过聚合酶链反应诊断,其余1只通过临床诊断。所有诊断为HSK的患者在接受白内障手术前均无该感染的既往临床病史。最初,所有15只眼均诊断为中毒性角膜炎,但最初15只眼中11只的最终诊断为上皮性疱疹性角膜炎。在我们的研究中,切口位置与HSK的发生有关(P<0.05)。
白内障手术后HSK上皮性角膜炎是一种相对少见的并发症,因其相对罕见,在疾病早期可能被误诊。本研究探讨了常规白内障手术中颞侧角膜穿透性切口入路可能会中断角膜神经,进而引发HSK复发的可能性。