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眼部手术后新发疱疹性眼病的不典型临床表现。

Unusual clinical presentations of new-onset herpetic eye disease after ocular surgery.

机构信息

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.

出版信息

Acta Ophthalmol. 2012 Sep;90(6):514-8. doi: 10.1111/j.1755-3768.2010.02060.x. Epub 2010 Dec 14.

Abstract

PURPOSE

To report five cases of new-onset herpetic eye disease with unusual presentation after ocular surgery.

METHODS

Herpetic eye disease was suspected in five cases, three after cataract surgery and two after lamellar corneal transplantation surgery. Of these, four cases presented within 2-6 weeks of surgery. The clinical presentation was in the form of an epithelial defect, suspected epithelial down growth, graft oedema with unexplained anterior chamber inflammation and graft-host interface infection. A swab for viral detection with real-time polymerase chain reaction was performed in all the described cases.

RESULTS

Herpes simplex disease was detected in all cases. All cases responded to the antiherpetic medications.

CONCLUSIONS

Our study shows that new-onset herpetic eye disease may occur after cataract surgery and lamellar corneal transplantation, and a high index of suspicion may be necessary for the diagnosis in such cases.

摘要

目的

报告 5 例眼部手术后新发生的表现不典型的疱疹性眼病。

方法

怀疑 5 例患者发生疱疹性眼病,其中 3 例在白内障手术后,2 例在板层角膜移植手术后。其中 4 例在手术后 2-6 周内出现。临床表现为上皮缺损、疑似上皮下生长、移植物水肿伴不明原因的前房炎症和移植物宿主界面感染。对所有描述的病例均进行了拭子病毒检测和实时聚合酶链反应。

结果

所有病例均检测到单纯疱疹病毒。所有病例均对抗疱疹药物有反应。

结论

我们的研究表明,白内障手术后和板层角膜移植后可能会发生新的疱疹性眼病,在这种情况下,可能需要高度怀疑以进行诊断。

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