Department of Health Science and Technology, Aalborg University, Frederik Bajers Vej 7A2, A2-208, 9220 Aalborg East, Denmark.
Toxins (Basel). 2018 Mar 29;10(4):143. doi: 10.3390/toxins10040143.
This review explores current evidence to demonstrate that botulinum neurotoxins (BoNTs) exert antipruritic effects. Both experimental and clinical conditions in which botulinum neurotoxins have been applied for pruritus relief will be presented and significant findings will be highlighted. Potential mechanisms underlying antipruritic effects will also be discussed and ongoing challenges and unmet needs will be addressed.
本综述探讨了目前的证据，以证明肉毒杆菌神经毒素（BoNTs）具有止痒作用。将介绍肉毒杆菌神经毒素用于缓解瘙痒的实验和临床情况，并强调重要发现。还将讨论止痒作用的潜在机制，并解决正在面临的挑战和未满足的需求。
