Suppr超能文献

第一届德国噬菌体研讨会-会议报告。

1st German Phage Symposium-Conference Report.

机构信息

Hohenheim Research Center for Health Sciences, University of Hohenheim, 70599 Stuttgart, Germany.

Institute of Microbiology, University of Hohenheim, 70599 Stuttgart, Germany.

出版信息

Viruses. 2018 Mar 29;10(4):158. doi: 10.3390/v10040158.

Abstract

In Germany, phage research and application can be traced back to the beginning of the 20th century. However, with the triumphal march of antibiotics around the world, the significance of bacteriophages faded in most countries, and respective research mainly focused on fundamental questions and niche applications. After a century, we pay tribute to the overuse of antibiotics that led to multidrug resistance and calls for new strategies to combat pathogenic microbes. Against this background, bacteriophages came into the spotlight of researchers and practitioners again resulting in a fast growing "phage community". In October 2017, part of this community met at the 1st German Phage Symposium to share their knowledge and experiences. The participants discussed open questions and challenges related to phage therapy and the application of phages in general. This report summarizes the presentations given, highlights the main points of the round table discussion and concludes with an outlook for the different aspects of phage application.

摘要

在德国,噬菌体的研究和应用可以追溯到 20 世纪初。然而,随着抗生素在世界范围内的广泛应用,噬菌体在大多数国家的重要性逐渐降低,相应的研究主要集中在基础问题和利基应用上。一个世纪后,我们对过度使用抗生素导致的多重耐药性表示敬意,并呼吁采取新的策略来对抗致病微生物。在此背景下,噬菌体再次成为研究人员和实践者的焦点,形成了一个快速发展的“噬菌体社区”。2017 年 10 月,该社区的一部分成员在第一届德国噬菌体研讨会上齐聚一堂,分享他们的知识和经验。与会者讨论了与噬菌体治疗和噬菌体一般应用相关的开放性问题和挑战。本报告总结了会议上的演讲,突出了圆桌讨论的要点,并对噬菌体应用的不同方面进行了展望。

相似文献

1
1st German Phage Symposium-Conference Report.
Viruses. 2018 Mar 29;10(4):158. doi: 10.3390/v10040158.
2
"French Phage Network" Annual Conference 2018-Fourth Meeting Report.
Viruses. 2019 May 23;11(5):470. doi: 10.3390/v11050470.
3
Phage Life Cycles Behind Bacterial Biodiversity.
Curr Med Chem. 2017 Nov 24;24(36):3987-4001. doi: 10.2174/0929867324666170413100136.
4
Interaction of phages, bacteria, and the human immune system: Evolutionary changes in phage therapy.
Rev Med Virol. 2019 Sep;29(5):e2055. doi: 10.1002/rmv.2055. Epub 2019 May 30.
5
"French Phage Network"-Third Meeting Report.
Viruses. 2018 Mar 10;10(3):123. doi: 10.3390/v10030123.
6
"French Phage Network" Annual Conference-Fifth Meeting Report.
Viruses. 2020 Apr 14;12(4):446. doi: 10.3390/v12040446.
7
Phages amid antimicrobial resistance.
Crit Rev Microbiol. 2019 Sep-Nov;45(5-6):701-711. doi: 10.1080/1040841X.2019.1691973. Epub 2019 Nov 27.
8
Formulation, stabilisation and encapsulation of bacteriophage for phage therapy.
Adv Colloid Interface Sci. 2017 Nov;249:100-133. doi: 10.1016/j.cis.2017.05.014. Epub 2017 May 14.
10
Back to the future: bacteriophages as promising therapeutic tools.
HLA. 2016 Mar;87(3):133-40. doi: 10.1111/tan.12742. Epub 2016 Feb 19.

引用本文的文献

1
Application of Phagotherapy in the Treatment of Burn Patients (Review).
Sovrem Tekhnologii Med. 2021;12(3):95-103. doi: 10.17691/stm2020.12.3.12. Epub 2020 Jun 28.
2
Viability of Bacteriophages in the Complex Hydrogel Wound Dressings .
Sovrem Tekhnologii Med. 2021;13(2):32-38. doi: 10.17691/stm2021.13.2.03. Epub 2021 Apr 30.
3
Approaches to optimize therapeutic bacteriophage and bacteriophage-derived products to combat bacterial infections.
Virus Genes. 2020 Apr;56(2):136-149. doi: 10.1007/s11262-020-01735-7. Epub 2020 Feb 8.
4

本文引用的文献

1
Antibiotic Treatment Leads to Fecal and Coliphage Expansion in Severely Malnourished Diarrhea Patients.
Cell Mol Gastroenterol Hepatol. 2017 Dec 13;5(3):458-460.e6. doi: 10.1016/j.jcmgh.2017.11.014. eCollection 2018 Mar.
3
The impact of bacteriophages on phyllosphere bacterial abundance and composition.
Mol Ecol. 2018 Apr;27(8):2025-2038. doi: 10.1111/mec.14542. Epub 2018 Mar 15.
4
Unexpected evolutionary benefit to phages imparted by bacterial CRISPR-Cas9.
Sci Adv. 2018 Feb 14;4(2):eaar4134. doi: 10.1126/sciadv.aar4134. eCollection 2018 Feb.
5
Lysogeny is prevalent and widely distributed in the murine gut microbiota.
ISME J. 2018 Apr;12(4):1127-1141. doi: 10.1038/s41396-018-0061-9. Epub 2018 Feb 7.
6
The Magistral Phage.
Viruses. 2018 Feb 6;10(2):64. doi: 10.3390/v10020064.
7
Bacteriophages of the Urinary Microbiome.
J Bacteriol. 2018 Mar 12;200(7). doi: 10.1128/JB.00738-17. Print 2018 Apr 1.
8
Systematic discovery of antiphage defense systems in the microbial pangenome.
Science. 2018 Mar 2;359(6379). doi: 10.1126/science.aar4120. Epub 2018 Jan 25.
9
Phage therapy in allergic disorders?
Exp Biol Med (Maywood). 2018 Mar;243(6):534-537. doi: 10.1177/1535370218755658. Epub 2018 Jan 23.
10
The Potential of Phage Therapy in Sepsis.
Front Immunol. 2017 Dec 11;8:1783. doi: 10.3389/fimmu.2017.01783. eCollection 2017.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验