Department of Chemistry & Organic Chemistry, Natural Products and Food Stuffs Unit (QOPNA), University of Aveiro, 3810-193 Aveiro, Portugal.
Departamento de Química Orgânica, Universidade Federal Fluminense, Niterói 24020-150, RJ, Brazil.
Molecules. 2018 Mar 29;23(4):792. doi: 10.3390/molecules23040792.
Carbene transfer reactions are very important transformations in organic synthesis, allowing the generation of structurally challenging products by catalysed cyclopropanation, cyclopropenation, carbene C-H, N-H, O-H, S-H, and Si-H insertion, and olefination of carbonyl compounds. In particular, chiral and achiral metalloporphyrins have been successfully explored as biomimetic catalysts for these carbene transfer reactions under both homogeneous and heterogeneous conditions. In this work the use of synthetic metalloporphyrins (MPorph, M = Fe, Ru, Os, Co, Rh, Ir, Sn) as homogeneous or heterogeneous catalysts for carbene transfer reactions in the last years is reviewed, almost exclusively focused on the literature since the year 2010, except when reference to older publications was deemed to be crucial.
卡宾转移反应在有机合成中非常重要，通过催化的环丙烷化、环丙烯化、卡宾 C-H、N-H、O-H、S-H 和 Si-H 插入以及羰基化合物的烯化反应，可以生成具有挑战性的结构产物。特别是，手性和非手性金属卟啉已被成功探索作为这些卡宾转移反应的仿生催化剂，在均相和多相条件下均有应用。在这项工作中，综述了近年来使用合成金属卟啉（MPorph，M = Fe、Ru、Os、Co、Rh、Ir、Sn）作为均相或多相催化剂进行卡宾转移反应的情况，几乎完全集中在 2010 年以后的文献上，除非认为参考较早的出版物至关重要。
