Grewling Łukasz, Jenerowicz Dorota, Bogawski Paweł, Smith Matt, Nowak Małgorzata, Frątczak Agata, Czarnecka-Operacz Magdalena
Laboratory of Aeropalynology, Faculty of Biology, Adam Mickiewicz University, Poznan, Poland.
Department of Dermatology, Poznan University of Medical Science, Poznan, Poland.
Postepy Dermatol Alergol. 2018 Feb;35(1):83-89. doi: 10.5114/ada.2018.73167. Epub 2018 Feb 20.
The role of long-distance transported (LDT) pollen in inducing new sensitization and affecting sensitization rates in -sensitized patients is unclear.
The aim of this study was to estimate the degree of cross-sensitization to a allergens in citizens of Poznan (Western Poland). This area is covered by extensive populations but does not currently have local populations.
Sera of 119 patients were tested by fluoroenzyme immunoassay (CAP-FEIA system) against pollen allergen extracts of and , an allergenic component of A. (), and an allergenic component of (). Skin prick tests (SPTs, = 86) were performed with pollen allergen extracts of and . and pollen in ambient air was collected (1996-2013) by a Hirst type volumetric trap sited at roof level (33 m).
The SPT showed that the prevalence of sensitization to and pollen exceeded 3.5%, and 10.5%, respectively. The measurements of IgE in blood serum (CAP-FEIA) revealed that among -sensitized patients 90.1% (20/22 patients) were concomitantly sensitized to . 59.1% (13/22) of these patients reacted to , suggesting primary sensitization to pollen. Only 2 (9.1%) patients were mono-sensitized to pollen extract, but surprisingly not to .
The LDT pollen had a negligible effect on the rate of sensitization to allergens in Poznan and did not increase the prevalence of sensitization to pollen in this region. However, the majority of patients showing hypersensitization to pollen might also present symptoms during elevated episodes of LDT of pollen.
远距离传播（LDT）花粉在诱导新的致敏反应以及影响已致敏患者的致敏率方面的作用尚不清楚。
本研究的目的是评估波兰西部波兹南市民对多种过敏原的交叉致敏程度。该地区人口密集，但目前没有当地的[具体物种]种群。
采用荧光酶免疫测定法（CAP - FEIA系统）对119例患者的血清进行检测，以检测针对[两种花粉名称]的花粉过敏原提取物、[一种蒿属植物过敏原成分名称]以及[另一种过敏原成分名称]的反应。对86例患者进行了皮肤点刺试验（SPT），使用[两种花粉名称]的花粉过敏原提取物。通过位于屋顶高度（33米）的赫斯特型容积式捕集器收集了1996 - 2013年期间环境空气中的[两种花粉名称]花粉。
皮肤点刺试验表明，对[第一种花粉名称]和[第二种花粉名称]花粉的致敏率分别超过3.5%和10.5%。血清IgE测量（CAP - FEIA）显示，在对[第一种花粉名称]致敏的患者中，90.1%（20/22例患者）同时对[第二种花粉名称]致敏。这些患者中有59.1%（13/22）对[第三种过敏原名称]有反应，提示对[第二种花粉名称]花粉的原发性致敏。只有2例（9.1%）患者对[第一种花粉名称]花粉提取物单致敏，但令人惊讶的是对[第三种过敏原名称]未致敏。
远距离传播的[第一种花粉名称]花粉对波兹南地区对[多种过敏原名称]过敏原的致敏率影响可忽略不计，且未增加该地区对[第二种花粉名称]花粉的致敏率。然而，大多数对[第二种花粉名称]花粉过敏的患者在远距离传播的[第一种花粉名称]花粉浓度升高期间也可能出现症状。
