Stanton J A, Miller M L, Johnson P, Davignon D L, Barr S C
Metropolitan Veterinary Hospital, Akron, Ohio 44321, USA.
Department of Clinical Science, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.
J Small Anim Pract. 2018 Jul;59(7):411-414. doi: 10.1111/jsap.12835. Epub 2018 Mar 30.
To describe the treatment of sinonasal aspergillosis with topical 1% clotrimazole solution in dogs with cribriform plate lysis.
This retrospective study includes data retrieval from medical records of dogs with sinonasal aspergillosis and cribriform plate lysis that underwent topical treatment with 1% clotrimazole solution.
Five dogs with sinonasal aspergillosis, cribriform plate lysis diagnosed on CT scans, and normal neurologic examinations were treated with a single (n=3) or multiple (n=2) infusions of clotrimazole solution. No dogs developed clinical neurologic disease after therapy.
In this study, a topical clotrimazole solution was not associated with adverse neurologic effects in neurologically normal dogs with sinonasal aspergillosis and cribriform plate lysis.
描述在患有筛板溶解的犬中使用1%克霉唑溶液局部治疗鼻-鼻窦曲霉菌病的情况。
这项回顾性研究包括从接受1%克霉唑溶液局部治疗的患有鼻-鼻窦曲霉菌病和筛板溶解的犬的病历中检索数据。
5只经CT扫描诊断为鼻-鼻窦曲霉菌病、筛板溶解且神经学检查正常的犬接受了单次（n = 3）或多次（n = 2）克霉唑溶液输注治疗。治疗后没有犬出现临床神经疾病。
在本研究中，对于患有鼻-鼻窦曲霉菌病和筛板溶解且神经学正常的犬，局部使用克霉唑溶液未产生不良神经学影响。
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