Khademvatan S, Majidiani H, Foroutan M, Hazrati Tappeh K, Aryamand S, Khalkhali H R
Cellular and Molecular Research Center & Department of Medical Parasitology and Mycology,Urmia University of Medical Sciences,Urmia,Iran.
Department of Parasitology,Faculty of Medical Sciences,Tarbiat Modares University,Tehran,Iran.
J Helminthol. 2019 Mar;93(2):131-138. doi: 10.1017/S0022149X18000275. Epub 2018 Apr 2.
Cystic echinococcosis (CE) caused by Echinococcus granulosus sensu lato (s.l.) is a significant zoonosis, especially in developing countries of the Middle East, with many studies focusing on CE genotypes in Iran. We performed a systematic review to determine the exact status of E. granulosus genotypes in the country. We explored English (Pubmed, Scopus, ISI Web of Science and Science Direct) and Persian (Magiran, Iran Medex and Scientific Information Database) databases along with Google Scholar. Our review included 73 studies published prior to the end of 2015. In total, 2952 animal (intermediate and definitive) hosts were examined, and the prevalent genotypes comprised G1 (92.75%) and G6 (4.53%) in sheep, cattle, camels, goats and buffaloes; G3 (2.43%) in five herbivore hosts and dogs; G7 (0.2%) in sheep and goats; and G2 (0.06%) in dogs. G1 was mostly dominant in West Azerbaijan, whereas G3 and G6 were identified most frequently in the provinces of Isfahan and Fars, respectively. Regarding human CE infection, 340 cases were reported from Iran, with the identified genotypes G1 (n = 320), G6 (n = 13) and G3 (n = 7). Most CE-infected humans originated from Isfahan province (168 cases), whereas the lowest number of infected persons was noted in Kerman province (two cases). The information obtained from this systematic review is central to better understanding the biological and epidemiological characteristics of E. granulosus s.l. genotypes in Iran, leading to more comprehensive control strategies.
由细粒棘球绦虫复合种（Echinococcus granulosus sensu lato，s.l.）引起的囊型包虫病（CE）是一种重要的人畜共患病，在中东的发展中国家尤为突出，许多研究聚焦于伊朗的CE基因型。我们进行了一项系统综述，以确定该国细粒棘球绦虫基因型的确切状况。我们检索了英文数据库（PubMed、Scopus、ISI Web of Science和ScienceDirect）、波斯文数据库（Magiran、Iran Medex和科学信息数据库）以及谷歌学术。我们的综述纳入了2015年底之前发表的73项研究。总共检查了2952只动物（中间宿主和终末宿主），流行基因型在绵羊、牛、骆驼、山羊和水牛中包括G1（92.75%）和G6（4.53%）；在五种食草动物宿主和犬类中为G3（2.43%）；在绵羊和山羊中为G7（0.2%）；在犬类中为G2（0.06%）。G1在西阿塞拜疆最为常见，而G3和G6分别在伊斯法罕省和法尔斯省最常被鉴定出。关于人类CE感染，伊朗报告了340例病例，鉴定出的基因型为G1（n = 320）、G6（n = 13）和G3（n = 7）。大多数CE感染人类来自伊斯法罕省（168例），而克尔曼省感染人数最少（2例）。从这项系统综述中获得的信息对于更好地了解伊朗细粒棘球绦虫复合种基因型的生物学和流行病学特征至关重要，有助于制定更全面的控制策略。
