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A model of two conformational forms of heparins/heparans suggested by infrared spectroscopy.

作者信息

Grant D, Long W F, Williamson F B

机构信息

Department of Biochemistry, University of Aberdeen, Marischal College, U.K.

出版信息

Med Hypotheses. 1987 Oct;24(2):131-6. doi: 10.1016/0306-9877(87)90095-8.

DOI:10.1016/0306-9877(87)90095-8
PMID:2960871
Abstract

Results of infrared spectroscopy of complexes between cations and heparins, heparans and chemically-modified polymers suggest the existence of two conformational forms of heparins/heparans, differing in their modes of interaction with cations. Functions of heparans at normal and cancer cell surfaces are discussed in the light of this model.

摘要

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