A model of two conformational forms of heparins/heparans suggested by infrared spectroscopy.
作者信息
Grant D, Long W F, Williamson F B
机构信息
Department of Biochemistry, University of Aberdeen, Marischal College, U.K.
出版信息
Med Hypotheses. 1987 Oct;24(2):131-6. doi: 10.1016/0306-9877(87)90095-8.
PMID:2960871
Abstract
Results of infrared spectroscopy of complexes between cations and heparins, heparans and chemically-modified polymers suggest the existence of two conformational forms of heparins/heparans, differing in their modes of interaction with cations. Functions of heparans at normal and cancer cell surfaces are discussed in the light of this model.
摘要
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