肝素 - 阳离子复合物的红外光谱
Infrared spectroscopy of heparin-cation complexes.
作者信息
Grant D, Long W F, Williamson F B
机构信息
Department of Biochemistry, University of Aberdeen, Marischal College, U.K.
出版信息
Biochem J. 1987 May 15;244(1):143-9. doi: 10.1042/bj2440143.
Abstract
Hydrated and partially hydrated films and aqueous solutions of heparin, heparans and N-desulphated preparations of these polymers were studied by near- and fundamental-region-i.r. spectroscopy in the presence of a range of countercations. The results suggest that ion binding is not explicable solely in terms of simple electrostatic theory, and that specific cation effects, and the hydration pattern of the polymer-cation complex need to be taken into account.
摘要
通过近红外和基频红外光谱法，在一系列抗衡阳离子存在的情况下，对肝素、硫酸乙酰肝素及其N - 去硫酸化制剂的水合和部分水合薄膜及水溶液进行了研究。结果表明，离子结合不能仅用简单的静电理论来解释，还需要考虑特定阳离子效应以及聚合物 - 阳离子复合物的水合模式。
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