Icahn School of Medicine at Mount Sinai, New York, New York (M.L.).
Ann Intern Med. 2018 Apr 3;168(7):ITC49-ITC64. doi: 10.7326/AITC201804030.
Psoriasis, an inherited disorder of the immune system, presents most commonly in the skin and joints but is also associated with cardiovascular, metabolic, and neuropsychiatric effects. Treatments include topical therapy for mild disease; phototherapy and oral therapy, such as retinoids and immunomodulating agents; and targeted biologic therapies that have revolutionized treatment of psoriasis and psoriatic arthritis. Primary care physicians should be aware of the systemic associations of psoriasis and the treatments available for this disorder.
银屑病，一种遗传性免疫系统疾病，通常表现在皮肤和关节上，但也与心血管、代谢和神经精神方面的影响有关。治疗方法包括轻度疾病的局部治疗；光疗和口服治疗，如类视黄醇和免疫调节剂；以及靶向生物疗法，这些疗法彻底改变了银屑病和银屑病关节炎的治疗方法。初级保健医生应该了解银屑病的系统关联以及这种疾病的可用治疗方法。
