Gnat S, Majer-Dziedzic B, Nowakiewicz A, Trościańczyk A, Ziółkowska G, Jesionek W, Choma I, Dziedzic R, Zięba P
University of Life Sciences, Faculty of Veterinary Medicine, Institute of Biological Bases of Animal Diseases, Sub-Department of Veterinary Microbiology, Akademicka 12, 20-033 Lublin, Poland.
University of Maria Curie-Skłodowska, Faculty of Chemistry, Department of Chromatographic Methods, Maria Curie-Skłodowska sq. 3, 20-031 Lublin, Poland.
Pol J Vet Sci. 2017 Dec;20(4):697-706. doi: 10.1515/pjvs-2017-0087.
Antibacterial activity is the most widely studied aspect of plant extracts. Antibiotics extensively produced and consumed in large quantities, have proved to be problematic due to various types of adverse effects. The development of bacterial resistance to currently available antibiotics has necessitated the search for new antibacterial agents. One of the alternative strategies for fighting antibiotic- resistant bacteria is the use of natural antimicrobial substances such as plant extracts. We tested the antimicrobial activity of nine extracts from different plants against pathogenic bacteria isolated from the faeces of red deer (Cervus elaphus). Selected bacteria commonly contaminated the natural environment and constitute a source of infection in other animals and humans. Extracts obtained from the following plants were tested: Hypericum perforatum L., Chamomilla recutita L., Achillea millefolium L., Salvia officinalis L., Thymus vulgaris L., Pinus sylvestris L., Mentha x piperita L., Valeriana officinalis L. and Foeniculum vulgare Mill. The highest degree of antibacterial properties was observed for Mentha x piperita L., narrower spectrum of activity possessed Hypericum perforatum L. Extracts of Achillea millefolium L. had the lowest spectrum of antibacterial activity. Our study confirms that many plant extracts shows in vitro antibacterial activity.
抗菌活性是植物提取物研究最为广泛的一个方面。大量生产和消费的抗生素，由于各种不良反应已被证明存在问题。细菌对现有抗生素产生耐药性，因此有必要寻找新的抗菌剂。对抗生素耐药菌的一种替代策略是使用天然抗菌物质，如植物提取物。我们测试了九种不同植物提取物对从马鹿（Cervus elaphus）粪便中分离出的病原菌的抗菌活性。选定的细菌通常污染自然环境，并构成其他动物和人类的感染源。测试了从以下植物中获得的提取物：贯叶连翘（Hypericum perforatum L.）、洋甘菊（Chamomilla recutita L.）、蓍草（Achillea millefolium L.）、鼠尾草（Salvia officinalis L.）、百里香（Thymus vulgaris L.）、欧洲赤松（Pinus sylvestris L.）、薄荷（Mentha x piperita L.）、缬草（Valeriana officinalis L.）和茴香（Foeniculum vulgare Mill.）。薄荷（Mentha x piperita L.）的抗菌性能最强，贯叶连翘（Hypericum perforatum L.）的活性谱较窄。蓍草（Achillea millefolium L.）提取物的抗菌活性谱最低。我们的研究证实，许多植物提取物在体外具有抗菌活性。
