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奶酪中的甲萘醌含量。

Menaquinone Content of Cheese.

机构信息

R&D Group VitaK, Maastricht University, Oxfordlaan 55, 6229 EV Maastricht, The Netherlands.

出版信息

Nutrients. 2018 Apr 4;10(4):446. doi: 10.3390/nu10040446.

DOI:10.3390/nu10040446
PMID:29617314
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5946231/
Abstract

Vitamin K₂ (menaquinone) concentrations were measured in a wide range of cheeses and the effects of fat content, ripening and origin of the cheeses were investigated. Moreover, the menaquinone content of cheese was compared with that of other foods known to contain vitamin K₂. It was found that cheese and curd are the most important sources of long-chain menaquinones in the Western diet and, in general, hard cheeses are richer in menaquinones than soft cheeses. However, the actual menaquinone content varies substantially and is dependent on the type of cheese, the time of ripening, the fat content and the geographic area where the cheeses are produced. Given the fact that poor vitamin K status has been mentioned as a risk factor for cardiovascular disease and mortality, while there is no clear evidence for adverse cardiovascular effects of dairy fats, cheese should be considered as a recommendable component in a heart-healthy diet.

摘要

维生素 K₂(甲萘醌)的浓度在各种奶酪中进行了测量,并研究了脂肪含量、成熟度和奶酪来源的影响。此外,还比较了奶酪中的甲萘醌含量与其他已知含有维生素 K₂的食物。结果发现,奶酪和凝乳是西方饮食中长链甲萘醌的最重要来源,而且一般来说,硬奶酪比软奶酪含有更丰富的甲萘醌。然而,实际的甲萘醌含量差异很大,取决于奶酪的类型、成熟时间、脂肪含量以及奶酪生产的地理位置。鉴于维生素 K 状态不佳被认为是心血管疾病和死亡率的一个风险因素,而乳制品脂肪对心血管没有明显的不良影响,因此奶酪应该被认为是心脏健康饮食中可推荐的成分。

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本文引用的文献

1
Multiple Vitamin K Forms Exist in Dairy Foods.乳制品中存在多种维生素K形式。
Curr Dev Nutr. 2017 Jun 1;1(6):e000638. doi: 10.3945/cdn.117.000638. eCollection 2017 Jun.
2
The relationship between vitamin K and peripheral arterial disease.维生素 K 与外周动脉疾病的关系。
Atherosclerosis. 2016 Sep;252:15-20. doi: 10.1016/j.atherosclerosis.2016.07.915. Epub 2016 Jul 25.
3
Measurement of Multiple Vitamin K Forms in Processed and Fresh-Cut Pork Products in the U.S. Food Supply.美国食品供应中加工和新鲜切割猪肉产品中多种维生素 K 形式的测量。
J Agric Food Chem. 2016 Jun 8;64(22):4531-5. doi: 10.1021/acs.jafc.6b00938. Epub 2016 May 24.
4
Impact of menaquinone-4 supplementation on coronary artery calcification and arterial stiffness: an open label single arm study.补充维生素K2对冠状动脉钙化和动脉僵硬度的影响:一项开放标签单臂研究。
Nutr J. 2016 May 12;15(1):53. doi: 10.1186/s12937-016-0175-8.
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The abnormal status of uncarboxylated matrix Gla protein species represents an additional mortality risk in heart failure patients with vascular disease.未羧化基质Gla蛋白种类的异常状态是患有血管疾病的心力衰竭患者的又一死亡风险。
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Yogurt drink fortified with menaquinone-7 improves vitamin K status in a healthy population.添加了维生素K2的酸奶饮料可改善健康人群的维生素K状况。
J Nutr Sci. 2015 Oct 16;4:e35. doi: 10.1017/jns.2015.25. eCollection 2015.
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Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies.饱和脂肪酸和反式不饱和脂肪酸的摄入量与全因死亡率、心血管疾病及2型糖尿病风险:观察性研究的系统评价与荟萃分析
BMJ. 2015 Aug 11;351:h3978. doi: 10.1136/bmj.h3978.
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Desphospho-uncarboxylated matrix Gla protein is associated with increased aortic stiffness in a general population.去磷酸化未羧化基质γ-羧基谷氨酸蛋白与普通人群中主动脉僵硬度增加有关。
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Nutr Rev. 2015 May;73(5):259-75. doi: 10.1093/nutrit/nuu060. Epub 2015 Mar 29.