Tandon Rimpy, Jain Arihant, Malhotra Pankaj
1Department of Obstetrics and Gynaecology, Government Medical College and Hospital-32, Chandigarh, India.
2Department of Internal Medicine (Clinical Hematology Division), PGIMER, Chandigarh, India.
Indian J Hematol Blood Transfus. 2018 Apr;34(2):204-215. doi: 10.1007/s12288-018-0949-6. Epub 2018 Mar 14.
Iron deficiency anemia (IDA) continues to be the commonest etiology of anemia in pregnancy. The prevalence of iron deficiency (ID) in pregnant Indian women is amongst the highest in the world. Untreated iron deficiency (ID) has significant adverse feto-maternal consequences. Plethora of investigations are available for diagnosis of IDA, each having specific advantages and disadvantages when used in the pregnancy setting. Therapy for ID includes dietary modification, oral iron supplementation, intravenous iron and blood transfusion. Newer parenteral iron preparations are safe and there is mounting evidence to suggest their use in frontline settings for pregnancy associated IDA in the second and third trimester. Through this review, we suggest an algorithm for diagnosis and treatment of IDA in pregnancy depending on the severity of anemia and period of gestation suited for widespread use in resource limited settings. Also, we recommend ways for increasing public awareness and tackling this health issue including the observance of "National Anemia Awareness and Treatment Day."
缺铁性贫血(IDA)仍然是妊娠期贫血最常见的病因。印度孕妇缺铁(ID)的患病率位居世界前列。未经治疗的缺铁会对母婴产生重大不良后果。有多种检查方法可用于诊断IDA,在妊娠期使用时每种方法都有其特定的优缺点。缺铁的治疗方法包括饮食调整、口服铁剂补充、静脉补铁和输血。新型肠外铁剂制剂是安全的,越来越多的证据表明可在妊娠中期和晚期将其用于一线治疗妊娠相关的IDA。通过本综述,我们根据贫血的严重程度和妊娠时期,提出了一种妊娠期IDA的诊断和治疗方案,适用于资源有限地区广泛使用。此外,我们还推荐了提高公众意识和解决这一健康问题的方法,包括设立“全国贫血宣传与治疗日”。