Liow Eric, Kassam Rosemin, Sekiwunga Richard
School of Population and Public Health, Faculty of Medicine, University of British Columbia, 2206 East Mall, Vancouver, BC, Canada V6T 1Z3.
Child Health and Development Centre, School of Medicine, Makerere University, P.O. Box 7062, Kampala, Uganda.
J Trop Med. 2018 Feb 12;2018:6987435. doi: 10.1155/2018/6987435. eCollection 2018.
This study investigated unlicensed drug outlets' practices for the management of malaria in the rural district of Butaleja, Uganda. A qualitative design using semistructured interviews was used. Interviews were recorded, translated, transcribed, and analyzed using thematic analysis. A total of 75 vendors, representing 85% of the outlets in the study area, were interviewed. Most of the vendors were associated with a drug shop type of outfit. About three-quarters reported having completed some level of postsecondary education, but just one-tenth of the vendors had qualifications that made them eligible to apply for a license to operate a drug shop. While most outlets stocked at least one type of antimalarial, only about one-quarter stocked an artemisinin-based combination therapy (ACT), one-quarter expressed a preference for ACTs, and less than one-tenth attested to firmly adhering to the national malaria treatment guidelines on dispensing ACTs as the first-line option. In contrast, nine out of 10 vendors stocked quinine and well over a third stocked antimalarials no longer recommended, such as chloroquine and sulphadoxine-pyrimethamine. Given the ongoing gap between the national malaria policy and unlicensed drug outlet practices, this study calls for greater engagement of unlicensed vendors to improve the management of childhood malaria.
本研究调查了乌干达布塔莱贾农村地区无证药品销售点的疟疾管理做法。采用了使用半结构化访谈的定性设计。访谈进行了录音、翻译、转录,并使用主题分析法进行分析。共采访了75名摊贩,占研究区域内销售点的85%。大多数摊贩与药店类型的机构有关联。约四分之三的摊贩报告称完成了一定程度的高等教育,但只有十分之一的摊贩具备使其有资格申请药店经营许可证的资质。虽然大多数销售点至少储备了一种抗疟药,但只有约四分之一储备了以青蒿素为基础的联合疗法(ACT),四分之一表示倾向于使用ACT,不到十分之一的人证明严格遵守国家疟疾治疗指南,将ACT作为一线用药。相比之下,十分之九的摊贩储备了奎宁,超过三分之一的摊贩储备了不再推荐使用的抗疟药,如氯喹和磺胺多辛-乙胺嘧啶。鉴于国家疟疾政策与无证药品销售点做法之间仍存在差距,本研究呼吁加强与无证摊贩的合作,以改善儿童疟疾的管理。