粪产碱杆菌菌株JQ135的全基因组序列，该菌株能够高效降解烟酸。
Complete Genome Sequence of Alcaligenes Faecalis Strain JQ135, a Bacterium Capable of Efficiently Degrading Nicotinic Acid.
作者信息
Zhang Yanting, Chen Qing, Ji Junbin, Zhao Lingling, Zhang Lei, Qiu Jiguo, He Jian
机构信息
Key Laboratory of Agricultural Environmental Microbiology, Ministry of Agriculture, College of Life Sciences, Nanjing Agricultural University, Nanjing, 210095, China.
College of Life Sciences, Zaozhuang University, Zaozhuang, 277160, China.
出版信息
Curr Microbiol. 2018 Dec;75(12):1551-1554. doi: 10.1007/s00284-018-1486-0. Epub 2018 Apr 5.
Nicotinic acid (NA), known as vitamin B3, is ubiquitous in nature and plays an important role in living organisms. The microbial catabolism of NA is highly diverse. However, the NA degradation by Alcaligenes faecalis strains has been poorly investigated. In this study, we report the complete genome sequence of A. faecalis JQ135 (4.08 Mbp) and several essential genes for NA degradation. This genome sequence will facilitate to elucidate the molecular metabolism of NA and advance the potential biotechnological applications of A. faecalis strains.
烟酸（NA），即维生素B3，在自然界中广泛存在，在生物体中发挥着重要作用。NA的微生物分解代谢具有高度多样性。然而，粪产碱杆菌菌株对NA的降解研究较少。在本研究中，我们报告了粪产碱杆菌JQ135的完整基因组序列（4.08 Mbp）以及几个NA降解必需基因。该基因组序列将有助于阐明NA的分子代谢，并推进粪产碱杆菌菌株潜在的生物技术应用。
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