20世纪90年代在日本分离出的6株猫轮状病毒A毒株的完整基因型组合，其中包括一种罕见的A15 NSP1基因型。
Full genotype constellations of six feline Rotavirus A strains isolated in Japan in the 1990s including a rare A15 NSP1 genotype.
作者信息
Nakagomi Toyoko, Agbemabiese Chantal Ama, Nakagomi Osamu
机构信息
Department of Molecular Epidemiology, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.
出版信息
Arch Virol. 2018 Aug;163(8):2257-2260. doi: 10.1007/s00705-018-3835-5. Epub 2018 Apr 5.
Full genome sequencing of six feline Rotavirus A (RVA) strains isolated in Japan in the 1990s revealed three genotype constellations, one of which had a unique constellation of G3-P[3]-I3-R3-C3-M3-A15-N3-T3-E3-H6. Genotype A15, carried by RVA/Cat-tc/JPN/FRV348/1994/G3P[3], is a rare NSP1 genotype, and only one human and one canine RVA strains have thus far been reported to carry this genotype. The other three G3P[3] strains (FRV72, FRV73, and FRV303) possessed a constellation of I3-R3-C2-M3-A9-N2-T3-E3-H6, whereas two G3P[9] strains (FRV317 and FRV384) possessed a constellation of I3-R3-C3-M3-A3-N3-T3-E3-H3.
对20世纪90年代在日本分离出的6株猫轮状病毒A（RVA）进行全基因组测序，结果显示出三种基因型组合，其中一种具有独特的G3-P[3]-I3-R3-C3-M3-A15-N3-T3-E3-H6组合。RVA/Cat-tc/JPN/FRV348/1994/G3P[3]携带的A15基因型是一种罕见的NSP1基因型，迄今为止，仅报道过一株人类RVA毒株和一株犬类RVA毒株携带该基因型。其他三株G3P[3]毒株（FRV72、FRV73和FRV303）具有I3-R3-C2-M3-A9-N2-T3-E3-H6组合，而两株G3P[9]毒株（FRV317和FRV384）具有I3-R3-C3-M3-A3-N3-T3-E3-H3组合。
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