Nguyen Daniel, Alsaati Farah, Deitrick Jena, Azhar Kamel, Sbar Evelyn
Texas Tech University Health Sciences Center Amarillo School of Medicine, 1400 S Coulter St, Amarillo, TX, 79106, USA.
Auto Immun Highlights. 2018 Apr 6;9(1):5. doi: 10.1007/s13317-018-0105-1.
Systemic lupus erythematous (SLE) is a systemic auto-immune disorder with a variety of presentations and wide spread organ involvement. We present a case report of a patient with an SLE exacerbation as well as concurrent rhabdomyolysis with massively elevated CPK (304,700 U/L). Though a rarely reported effect of SLE, rhabdomyolysis can be severe and potentially lethal secondary or concurrent to an acute SLE episode. This case report demonstrates the association between SLE and rhabdomyolysis, which is not well described in the current literature.
系统性红斑狼疮(SLE)是一种全身性自身免疫性疾病,有多种临床表现且广泛累及器官。我们报告一例系统性红斑狼疮加重并发横纹肌溶解症且肌酸磷酸激酶(CPK)大幅升高(304,700 U/L)的病例。尽管横纹肌溶解症是系统性红斑狼疮一种罕见的表现,但在急性系统性红斑狼疮发作继发或并发时可能很严重且有潜在致命性。本病例报告展示了系统性红斑狼疮与横纹肌溶解症之间的关联,这在当前文献中描述不多。