Kabir Ali, Mousavi Sara, Pazouki Abdolreza
Minimally Invasive Surgery Research Center; Iran University of Medical Sciences, Tehran, Iran.
Center of Excellence for Minimally Invasive Surgery Training, Iran University of Medical Sciences, Tehran, Iran.
Curr Diabetes Rev. 2019;15(1):49-61. doi: 10.2174/1573399814666180403164529.
In this Meta-analysis, we aimed to quantify the incidence of complications of different methods of bariatric surgery on diabetic patients.
Type 2 Diabetes Mellitus (T2DM) is increasing worldwide specifically in obese cases. Additionally, obesity worsens T2DM. Complications of each bariatric surgery method were assessed separately; but, a meta-analysis of these complications and comparison between procedures in T2DM patients have not been investigated previously. The result of this study will help surgeons to choose the most appropriate surgical technique, considering individual conditions for a diabetic patient.
We searched PubMed, Scopus, and ISI for original papers including bariatric surgical procedures for diabetic population and the reported consequences. Data analyses were done using Stata software.
Mortality percentage between diabetic and non-diabetic patients was statistically nonsignificant (P = 0.987). Early and late complications were higher in diabetic group in comparison with non-diabetic (6.0% vs. 1.8%, P = 0.024 and 0.6% vs. 0.3%, P = 0.04, respectively). Most prevalent findings in malabsorptive (7.8%, P < 0.001) and restrictive procedures (80%, P < 0.001) were major complications and hypoglycemic episodes, respectively.
As our study showed, most of the complications are not necessarily higher in diabetic population but dependent on the method of surgery.
在本荟萃分析中，我们旨在量化不同减肥手术方法对糖尿病患者并发症的发生率。
2型糖尿病（T2DM）在全球范围内呈上升趋势，尤其是在肥胖患者中。此外，肥胖会使T2DM病情恶化。此前已分别评估了每种减肥手术方法的并发症；但是，尚未对这些并发症进行荟萃分析，也未对T2DM患者不同手术方法之间进行比较。本研究结果将有助于外科医生根据糖尿病患者的个体情况选择最合适的手术技术。
我们在PubMed、Scopus和ISI中检索了包括针对糖尿病患者的减肥手术程序及所报告后果的原始论文。使用Stata软件进行数据分析。
糖尿病患者和非糖尿病患者之间的死亡率百分比在统计学上无显著差异（P = 0.987）。与非糖尿病患者相比，糖尿病组的早期和晚期并发症更高（分别为6.0%对1.8%，P = 0.024；0.6%对0.3%，P = 0.04）。在吸收不良手术（7.8%，P < 0.001）和限制性手术（80%，P < 0.001）中，最常见的结果分别是主要并发症和低血糖发作。
正如我们的研究所显示，大多数并发症在糖尿病患者中不一定更高，而是取决于手术方法。
