少脉山油柑中的新型苯乙酮衍生物及其抗炎和抗氧化活性。
New Acetophenone Derivatives from Acronychia oligophlebia and Their Anti-inflammatory and Antioxidant Activities.
作者信息
Chen Neng-Hua, Li Wen, Zhong Yuan-Lin, Niu Qian-Wen, Li Ying-Ying, Zhang Yu-Bo, Li Man-Mei, Li Yao-Lan, Wang Guo-Cai
机构信息
Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou, 510632, P. R. China.
Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, 510632, P. R. China.
出版信息
Chem Biodivers. 2018 May;15(5):e18000080. doi: 10.1002/cbdv.201800080. Epub 2018 May 3.
Seven new acetophenone derivatives (acroliones A - G, 1 - 7) and three known ones (8 - 10) were isolated from the leaves of Acronychia oligophlebia. Their structures were elucidated based on extensive spectroscopic analyses (IR, UV, HR-ESI-MS, 1D- and 2D-NMR), X-ray diffraction and comparison with literature data. The anti-inflammatory and antioxidant activities of all isolates were evaluated.
从少脉山油柑叶中分离得到7个新的苯乙酮衍生物（崖椒酮A - G，1 - 7）和3个已知化合物（8 - 10）。通过广泛的光谱分析（红外光谱、紫外光谱、高分辨电喷雾电离质谱、一维和二维核磁共振谱）、X射线衍射以及与文献数据比较确定了它们的结构。对所有分离得到的化合物进行了抗炎和抗氧化活性评价。
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