Su Chung-Ren, Kuo Ping-Chung, Wang Meei-Ling, Liou Meei-Jen, Damu Amooru G, Wu Tian-Shung
Department of Chemistry, National Cheng Kung University, Tainan, 701, Taiwan, Republic of China.
J Nat Prod. 2003 Jul;66(7):990-3. doi: 10.1021/np030054x.
Chemical investigation on the stem and root bark of Acronychia pedunculata has resulted in the isolation of five new acetophenones, namely, acronyculatins A (1), B (2), C (3), D (4), and E (5). The structures of these metabolites were established on the basis of their 1D and 2D NMR spectroscopic and mass spectrometric data and by CD spectroscopy. The antioxidant and antityrosinase activities of these five metabolites and acrovestone (6) were evaluated. Among these compounds, 6 showed marginal antioxidant and antityrosinase activities.
对山油柑茎皮和根皮进行化学研究，从中分离出5种新的苯乙酮，即山油柑素A（1）、B（2）、C（3）、D（4）和E（5）。这些代谢产物的结构是根据其一维、二维核磁共振光谱和质谱数据以及圆二色光谱确定的。对这5种代谢产物和山油柑酮（6）的抗氧化和抗酪氨酸酶活性进行了评估。在这些化合物中，6显示出微弱的抗氧化和抗酪氨酸酶活性。
