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如何应对急性心力衰竭中的充血问题。

How to tackle congestion in acute heart failure.

作者信息

Martens Pieter, Mullens Wilfried

机构信息

Department of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium.

Doctoral School for Medicine and Life Sciences, Hasselt University, Diepenbeek, Belgium.

出版信息

Korean J Intern Med. 2018 May;33(3):462-473. doi: 10.3904/kjim.2017.355. Epub 2018 Apr 11.

Abstract

Acute heart failure is a common complication of chronic heart failure and is associated with a high risk for subsequent mortality and morbidity. In 90% of case acute heart failure is the resultant of congestion, a manifestation of fluid build-up due to increased filling pressures. As residual congestion at discharge following an acute heart failure episodes is one of the strongest predictors of poor outcome, the goal of therapy should be to resolve congestion completely. Important to comprehend is that increased cardiovascular filling pressures are not solely the resultant of intravascular volume excess but can also be induced by a decreased venous capacitance. This review article focusses on the pathophysiology, diagnoses, and treatment of congestion in acute heart failure. A clear distinction is made between states of volume overload (intravascular volume excess) or volume redistribution (decreased venous capacitance) contributing to congestion in acute heart failure.

摘要

急性心力衰竭是慢性心力衰竭的常见并发症,与随后的高死亡率和发病率相关。在90%的病例中,急性心力衰竭是充血的结果,充血是由于充盈压升高导致液体蓄积的一种表现。由于急性心力衰竭发作后出院时的残余充血是不良预后的最强预测因素之一,治疗的目标应该是完全消除充血。需要理解的重要一点是,心血管充盈压升高不仅是血管内容量过多的结果,也可能由静脉容量减少引起。这篇综述文章聚焦于急性心力衰竭中充血的病理生理学、诊断和治疗。明确区分了导致急性心力衰竭充血的容量超负荷(血管内容量过多)状态或容量重新分布(静脉容量减少)状态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51c8/5943665/cc55cb64c405/kjim-2017-355f1.jpg

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