Cabral Ana C, Moura-Ramos Mariana, Castel-Branco Margarida, Fernandez-Llimos Fernando, Figueiredo Isabel V
Pharmacology and Pharmaceutical Care Laboratory, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.
Cognitive and Behavioural Center for Research and Intervention (CINEICC), Faculty of Psychology and Educational Sciences, University of Coimbra, Coimbra, Portugal.
Rev Port Cardiol (Engl Ed). 2018 Apr;37(4):297-303. doi: 10.1016/j.repc.2017.09.017. Epub 2018 Apr 5.
The 8-Item Morisky Medication Adherence Scale (MMAS-8) is one of the most widely used instruments to assess medication adherence, but a validated European Portuguese version of MMAS-8 does not exist. Our aim was to develop and validate a European Portuguese version of the MMAS-8.
A process of translation and back-translation of the original MMAS-8 was performed. The questionnaire was administered in nine community pharmacies and one public hospital between March 2014 and September 2015. Adult patients taking at least one antihypertensive drug were invited to participate. A confirmatory factor analysis was performed and internal consistency, convergent validity and concurrent validity were examined.
A total of 472 patients were enrolled in the study. The mean MMAS-8 score obtained was 6.74±1.39. One hundred and thirty-two patients were classified as low adherers (28%), 181 (38.3%) as medium adherers and 159 (33.7%) as high adherers. For the factorial structure of the Portuguese version of the MMAS-8, the fit indices of the final model (chi-square [18] 48.465, p<0.001) are suggestive of very good fit, with comparative fit index 0.95, root mean square error of approximation 0.06 (90% confidence interval 0.04-0.08), and standardized root mean square residual 0.04, confirming that the construct tested was unidimensional. The Cronbach's alpha for all items was 0.60, and the translated version presents convergent validity and concurrent validity.
A European Portuguese version of the MMAS-8 was created that maintained a similar structure to the original MMAS-8 and good psychometric properties.
8项版的莫利斯基药物依从性量表（MMAS - 8）是评估药物依从性最广泛使用的工具之一，但目前尚无经过验证的欧洲葡萄牙语版本的MMAS - 8。我们的目的是开发并验证欧洲葡萄牙语版本的MMAS - 8。
对原始的MMAS - 8进行了翻译和回译过程。2014年3月至2015年9月期间，在9家社区药房和1家公立医院发放了调查问卷。邀请正在服用至少一种抗高血压药物的成年患者参与。进行了验证性因素分析，并检验了内部一致性、收敛效度和同时效度。
共有472名患者纳入研究。获得的MMAS - 8平均得分为6.74±1.39。132名患者被归类为低依从者（28%），181名（38.3%）为中度依从者，159名（33.7%）为高依从者。对于葡萄牙语版MMAS - 8的因子结构，最终模型的拟合指数（卡方[18]48.465，p<0.001）表明拟合非常好，比较拟合指数为0.95，近似均方根误差为0.06（90%置信区间0.04 - 0.08），标准化均方根残差为0.04，证实所测试的结构是单维的。所有条目的Cronbach's α为0.60，翻译版本具有收敛效度和同时效度。
创建了欧洲葡萄牙语版的MMAS - 8，其结构与原始MMAS - 8相似，且具有良好的心理测量学特性。
