Al-Mufti Fawaz, Thabet Ahmad M, Singh Tarundeep, El-Ghanem Mohammad, Amuluru Krishna, Gandhi Chirag D
Department of Neurology, Neurosurgery, and Radiology, Rutgers University-Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Department of Neurosurgery, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.
Interv Neurol. 2018 Feb;7(1-2):118-136. doi: 10.1159/000484571. Epub 2018 Jan 12.
Intracerebral hemorrhage (ICH) represents 10-15% of all stroke cases in the US annually. Fewer than 40% of these patients ever reach long-term functional independence, and mortality rate is roughly 40% at 1 month. Due to the high morbidity and mortality rates after ICH, early detection of high-risk patients would be beneficial in directing the management course and goals of care. This review aims to discuss relevant clinical and radiographic characteristics that can serve as predictors of poor prognosis and examine their efficacy in predicting patient outcomes after ICH.
A literature review was conducted on various clinical and radiographic factors. They were examined for their predictive value in relation to ICH outcome. Studies that focused on each of these factors were included, and their results analyzed for trends with regard to incidence, patient outcome, and mortality rate.
In this review, we examined clinical and radiographic characteristics that have been found to be significantly associated to a varying degree with poor outcome. Clinical and radiographic predictors of poor patient outcome are invaluable when it comes to identifying high-risk patients and triaging accordingly as well as guiding decision-making.
在美国，脑出血（ICH）每年占所有中风病例的10%-15%。这些患者中不到40%能实现长期功能独立，1个月时的死亡率约为40%。由于脑出血后的高发病率和死亡率，早期发现高危患者将有助于指导治疗过程和护理目标。本综述旨在讨论可作为预后不良预测指标的相关临床和影像学特征，并检验它们在预测脑出血患者预后方面的有效性。
对各种临床和影像学因素进行了文献综述。研究了它们对脑出血预后的预测价值。纳入了关注这些因素中每一个因素的研究，并分析了其结果在发病率、患者预后和死亡率方面的趋势。
在本综述中，我们研究了已发现与不同程度不良预后显著相关的临床和影像学特征。在识别高危患者并据此进行分类以及指导决策时，患者预后不良的临床和影像学预测指标非常重要。
